中国科学院 国家纳米科学中心 导师陈春英介绍
作者:科大科院考研网 发表时间:2019-10-28 来源:研招办
中科院考研推荐链接:
陈春英 女 博导 国家纳米科学中心
电子邮件: chenchy@nanoctr.cn
通信地址: 北京市中关村北一条11号
邮政编码: 100190
部门/实验室:纳米生物效应与安全性研究室
研究领域
1、高效低毒抗肿瘤纳米药物的研制及作用机制研究;
2、典型纳米材料与生物体相互作用规律及影响因素;
3、生物体系纳米颗粒暴露和效应标志物研究;
4、易感人群环境污染物长期暴露的分子毒理学研究。
招生信息
招生专业
0703J1-纳米科学与技术
071009-细胞生物学
070322-生物无机化学
071009-细胞生物学
070322-生物无机化学
招生方向
纳米材料的生物效应与安全性评价
纳米材料在肿瘤诊疗中的应用
生物体系中纳米材料的分析检测
纳米材料在肿瘤诊疗中的应用
生物体系中纳米材料的分析检测
教育背景
1991-09--1996-11 华中理工大学 医学博士学位,导师徐辉碧教授
1987-09--1991-07 华中理工大学(现华中科技大学)化学系 学士学位
1987-09--1991-07 华中理工大学(现华中科技大学)化学系 学士学位
学历
-- 研究生
学位
-- 博士
工作经历
工作简历
2006-06~现在, 国家纳米科学中心, 研究员、博士生导师。
2001-09~2002-09,瑞典卡罗林斯卡大学,诺贝尔医学生物化学研究所。, 博士后研究工作。
1998-11~2006-05,中国科学院高能物理研究所, 中国科学院核分析技术重点实验室工作,历任副研究员和研究员。
1996-12~1998-11,中国科学院高能物理研究所, 中国科学院核分析技术重点实验室博士后,合作导师柴之芳院士。
2001-09~2002-09,瑞典卡罗林斯卡大学,诺贝尔医学生物化学研究所。, 博士后研究工作。
1998-11~2006-05,中国科学院高能物理研究所, 中国科学院核分析技术重点实验室工作,历任副研究员和研究员。
1996-12~1998-11,中国科学院高能物理研究所, 中国科学院核分析技术重点实验室博士后,合作导师柴之芳院士。
社会兼职
2016-01-01-今,Springer出版《Science Bulletin》, 副主编
2016-01-01-今,中国预防医学会卫生毒理专业委员会, 常务委员
2016-01-01-今,中华预防医学会肿瘤预防专业委员会, 委员
2015-01-01-今,Elsevier出版《NanoImpact》, 副主编
2015-01-01-今,英国RSC出版《Metallomics》, 编委
2015-01-01-今,中国药学会纳米药物专业委员会, 委员兼秘书长
2014-01-01-今,欧洲Informa Healthcare《Nanotoxicology》, 编委
2013-01-01-今,中国毒理学会, 理事
2013-01-01-今,英国 RSC出版《Toxicology Research》, 顾问编委
2013-01-01-今,欧洲BioMed Central出版《Particle and Fibre Toxicology》, 编委
2011-01-01-今,中国毒理学会纳米毒理学专业委员会, 副主任委员兼秘书长
2011-01-01-今,世界卫生组织 (WHO) 纳米环境健康专家组, 专家(中国共2名)
2016-01-01-今,中国预防医学会卫生毒理专业委员会, 常务委员
2016-01-01-今,中华预防医学会肿瘤预防专业委员会, 委员
2015-01-01-今,Elsevier出版《NanoImpact》, 副主编
2015-01-01-今,英国RSC出版《Metallomics》, 编委
2015-01-01-今,中国药学会纳米药物专业委员会, 委员兼秘书长
2014-01-01-今,欧洲Informa Healthcare《Nanotoxicology》, 编委
2013-01-01-今,中国毒理学会, 理事
2013-01-01-今,英国 RSC出版《Toxicology Research》, 顾问编委
2013-01-01-今,欧洲BioMed Central出版《Particle and Fibre Toxicology》, 编委
2011-01-01-今,中国毒理学会纳米毒理学专业委员会, 副主任委员兼秘书长
2011-01-01-今,世界卫生组织 (WHO) 纳米环境健康专家组, 专家(中国共2名)
教授课程
纳米能源环境材料
纳米生物技术
科学前沿进展名家系列讲座III
Nanobiotechnology 中丹学院
纳米生物医学系列讲座
纳米生物效应---- "杰青学者论坛"系列讲座
纳米生物技术
科学前沿进展名家系列讲座III
Nanobiotechnology 中丹学院
纳米生物医学系列讲座
纳米生物效应---- "杰青学者论坛"系列讲座
专利与奖励
奖励信息
(1) 2017 中科院第五届“十大杰出妇女”, , 院级, 2017
(2) 英国皇家化学学会会士, 其他, 2016
(3) 第十一届中国青年女科学家奖, , 其他, 2014
(4) 国家百千万人才工程,有突出贡献中青年专家, , 国家级, 2014
(5) 全球高引用科学家(2002-2012), , 其他, 2014
(6) 纳米材料的安全性研究, 二等奖, 国家级, 2012
(7) 中国标准化杰出人物和创新人物奖, 一等奖, 部委级, 2011
(8) 纳米材料的健康效应与安全性, 二等奖, 省级, 2008
(2) 英国皇家化学学会会士, 其他, 2016
(3) 第十一届中国青年女科学家奖, , 其他, 2014
(4) 国家百千万人才工程,有突出贡献中青年专家, , 国家级, 2014
(5) 全球高引用科学家(2002-2012), , 其他, 2014
(6) 纳米材料的安全性研究, 二等奖, 国家级, 2012
(7) 中国标准化杰出人物和创新人物奖, 一等奖, 部委级, 2011
(8) 纳米材料的健康效应与安全性, 二等奖, 省级, 2008
专利成果
( 1 ) 纳米颗粒的制备方法及用该方法制备的纳米颗粒, 发明, 2013, 第 1 作者, 专利号: ZL201010274003.6
( 2 ) 金纳米棒的修饰方法及金纳米棒-功能分子复合体, 发明, 2013, 第 1 作者, 专利号: ZL201010274005.5
( 3 ) 一种药物组合物及其制备方法和应用, 发明, 2013, 第 1 作者, 专利号: ZL201010591760.6
( 4 ) 药物组合物及其制备方法和应用, 发明, 2013, 第 1 作者, 专利号: ZL201010591754.0
( 5 ) 富勒烯衍生物的应用及其疫苗佐剂和疫苗制剂, 发明, 2015, 第 1 作者, 专利号: ZL201310357325.0
( 6 ) 一种聚(天冬氨酸-co-乳酸)-磷脂酰乙醇胺接枝聚合物及其制备方法和应用, 发明, 2013, 第 2 作者, 专利号: ZL201010591737.7
( 7 ) 一种接枝聚合物及其制备方法和用途, 发明, 2014, 第 2 作者, 专利号: ZL201110242270.X
( 8 ) 富勒烯衍生物在制备用于基因传递的载体中的应用, 发明, 2014, 第 1 作者, 专利号: ZL201010621120.5
( 9 ) 一种载药纳米粒子及其制备方法和应用, 发明, 2014, 第 1 作者, 专利号: ZL201110266839.6
( 10 ) 一种药物组合物及其制备方法和用途, 发明, 2017, 第 1 作者, 专利号: 201410443946.5
( 11 ) 透明质酸-胱胺-聚乳酸-羟基乙酸接枝聚合物及其制备方法, 发明, 2016, 第 2 作者, 专利号: ZL201410443535.6
( 12 ) 猪瘟、猪蓝耳病、猪传染性胃肠炎病毒检测试剂盒及检测方法, 发明, 2016, 第 1 作者, 专利号: ZL201310302447.X
( 13 ) 一种静电纺丝膜及其制备方法和应, 发明, 2017, 第 1 作者, 专利号: 201710385104.2
( 14 ) 一种具有吸附过滤功能的静电纺丝膜及其制备方法和应用, 发明, 2017, 第 1 作者, 专利号: 201710386651.2
( 2 ) 金纳米棒的修饰方法及金纳米棒-功能分子复合体, 发明, 2013, 第 1 作者, 专利号: ZL201010274005.5
( 3 ) 一种药物组合物及其制备方法和应用, 发明, 2013, 第 1 作者, 专利号: ZL201010591760.6
( 4 ) 药物组合物及其制备方法和应用, 发明, 2013, 第 1 作者, 专利号: ZL201010591754.0
( 5 ) 富勒烯衍生物的应用及其疫苗佐剂和疫苗制剂, 发明, 2015, 第 1 作者, 专利号: ZL201310357325.0
( 6 ) 一种聚(天冬氨酸-co-乳酸)-磷脂酰乙醇胺接枝聚合物及其制备方法和应用, 发明, 2013, 第 2 作者, 专利号: ZL201010591737.7
( 7 ) 一种接枝聚合物及其制备方法和用途, 发明, 2014, 第 2 作者, 专利号: ZL201110242270.X
( 8 ) 富勒烯衍生物在制备用于基因传递的载体中的应用, 发明, 2014, 第 1 作者, 专利号: ZL201010621120.5
( 9 ) 一种载药纳米粒子及其制备方法和应用, 发明, 2014, 第 1 作者, 专利号: ZL201110266839.6
( 10 ) 一种药物组合物及其制备方法和用途, 发明, 2017, 第 1 作者, 专利号: 201410443946.5
( 11 ) 透明质酸-胱胺-聚乳酸-羟基乙酸接枝聚合物及其制备方法, 发明, 2016, 第 2 作者, 专利号: ZL201410443535.6
( 12 ) 猪瘟、猪蓝耳病、猪传染性胃肠炎病毒检测试剂盒及检测方法, 发明, 2016, 第 1 作者, 专利号: ZL201310302447.X
( 13 ) 一种静电纺丝膜及其制备方法和应, 发明, 2017, 第 1 作者, 专利号: 201710385104.2
( 14 ) 一种具有吸附过滤功能的静电纺丝膜及其制备方法和应用, 发明, 2017, 第 1 作者, 专利号: 201710386651.2
出版信息
发表论文
(1) Multifunctional near-infrared dye-magnetic nanoparticles for bioimaging and cancer therapy., Cancer Letters, 2017, 通讯作者
(2) Poly (Vinylpyrollidone) and Selenocysteine Modified Bi2Se3 Nanoparticles Enhance Radiotherapy Efficacy in Tumor and Promote Radioprotection in Normal Tissues, Advanced Materials, 2017, 通讯作者
(3) Chiral Surface of Nanoparticles Determines the Orientation of Adsorbed Transferrin and its Interaction with Receptors., ACS Nano, 2017, 通讯作者
(4) Remote Control and Modulation of Cellular Events by Plasmonic Gold Nanoparticles: Implications and Opportunities for Biomedical Applications, ACS Nano, 2017, 通讯作者
(5) Interference of Steroidogenesis by Gold Nanorod Core/Silver Shell Nanostructures: Implications for Reproductive Toxicity of Silver, Small, 2017, 通讯作者
(6) Interference of Steroidogenesis by Gold Nanorod Core/Silver Shell Nanostructures: Implications for Reproductive Toxicity of Silver, Small, 2017, 通讯作者
(7) A combined experimental and numerical study on upper airway dosimetry of inhaled nanoparticles from an electrical discharge machine shop, Particle and Fibre Toxicology, 2017, 通讯作者
(8) In vivo aggregation-induced transition between T1 and T2 relaxations of magnetic ultra-small iron oxide nanoparticles in tumor microenvironment., Nanoscale, 2017, 通讯作者
(9) Design of TPGS-functionalized Cu3BiS3 nanocrystals with strong absorption in the second near-infrared window for radiation therapy enhancement, Nanoscale, 2017, 通讯作者
(10) Light-Enhanced Antibacterial Activity of Graphene Oxide, Mainly via Accelerated Electron Transfer, Environmental Science & Technology, 2017, 通讯作者
(11) Fullerenol inhibits the cross-talk between bone marrow-derived mesenchymal stem cells and tumor cells by regulating MAPK signaling, Nanomedicine: Nanotechnology, Biology and Medicine, 2017, 通讯作者
(12) Mussel Inspired Polynorepinephrine Functionalized Electrospun Polycaprolactone Microfibers for Muscle Regeneration., Scientific Reports, 2017, 通讯作者
(13) Protein corona in vivo: dynamic complement proteins-mediated opsonization and immune modulation., Science Bulletin, 2017, 通讯作者
(14) Role of nanotechnology in HIV/AIDS vaccine development, Advanced Drug Delivery Reviews, 2016, 通讯作者
(15) Superstable Magnetic Nanoparticles in Conjugation with Near-Infrared Dye as a Multimodal Theranostic Platform, ACS Applied Materials & Interfaces, 2016, 通讯作者
(16) Rapid Degradation and High Renal Clearance of Cu3BiS3 Nanodots for Efficient Cancer Diagnosis and Photothermal Therapy in Vivo, ACS Nano, 2016, 通讯作者
(17) A Versatile Imaging and Therapeutic Platform Based on Dual-Band Luminescent Lanthanide Nanoparticles toward Tumor Metastasis Inhibition, ACS Nano, 2016, 通讯作者
(18) An experimental and computational approach to the development of ZnO nanoparticles that are safe by design, Small, 2016, 通讯作者
(19) Beyond PM2.5: The role of ultrafine particles on adverse health effects of air pollution, BBA - General Subjects, 2016, 通讯作者
(20) Silver nanoparticles induced oxidative and endoplasmic reticulum stresses in mouse tissues: implications for the development of acute toxicity after intravenous administration, Toxicology Research, 2016, 通讯作者
(21) Gold Nanomaterials in Consumer Cosmetics Nanoproducts: Analyses, Characterization and Dermal Safety Assessment, Small, 2016, 通讯作者
(22) Using Hollow Carbon Nanospheres as a Light-induced Free Radical Generator to Overcome Chemotherapy Resistance., Journal of the American Chemical Society, 2015, 通讯作者
(23) Core–Shell Upconversion Nanoparticle@Metal–Organic Framework Nanoprobes for Luminescent/Magnetic Dual-Mode Targeted Imaging, Advanced Materials, 2015, 通讯作者
(24) Use of Synchrotron Radiation-Analytical Techniques to Reveal Chemical Origin of Silver-Nanoparticle Cytotoxicity, ACS Nano, 2015, 通讯作者
(25) Bismuth Sulfide Nanorods as a Precision Nanomedicine for in Vivo Multimodal Imaging-Guided Photothermal Therapy of Tumor, ACS Nano, 2015, 通讯作者
(26) Near Infrared Laser Induced Targeted Cancer Therapy Using Thermo-Responsive Polymer Encapsulated Gold Nanorods, JACS, 2014, 通讯作者
(27) Endoplasmic Reticulum Stress Induced by Zinc Oxide Nanoparticles Is an Earlier Biomarker for Nanotoxicological Evaluation, ACS Nano, 2014, 通讯作者
(28) Novel Insights into Combating Cancer Chemotherapy Resistance Using a Plasmonic Nanocarrier: Enhancing Drug Sensitiveness and Accumulation Simultaneously with Localized Mild Photothermal Stimulus of Femtosecond Pulsed Laser, Advanced Functional Materials, 2014, 通讯作者
(29) Inhibition of Cancer Cell Migration by Gold Nanorods: Molecular Mechanisms and Implications for Cancer Therapy, Advanced Functional Materials, 2014, 通讯作者
(30) Polyhydroxylated Metallofullerenols Stimulate IL-1 Secretion of Macrophage through TLRs/MyD88/NF-κB Pathway and NLRP3 Inflammasome Activation, Small, 2014, 通讯作者
(31) Selective inhibition of breast cancer stem cells by gold nanorods mediated plasmonic hyperthermia, Biomaterials, 2014, 通讯作者
(32) Understanding the Toxicity of Carbon Nanotubes, Accounts of Chemical Research, 2013, 通讯作者
(33) Advanced nuclear analytical and related techniques for the growing challenges in nanotoxicology, Chemical Society Reviews, 2013, 第 1 作者
(34) Revealing the Binding Structure of the Protein Corona on Gold Nanorods Using Synchrotron Radiation-Based Techniques: Understanding the Reduced Damage in Cell Membranes, JACS, 2013, 通讯作者
(35) Morphologically Virus-like Fullerenol Nanoparticles Act as the Dual-functional Nanoadjuvant for HIV-1 Vaccine, Advanced Materials, 2013, 通讯作者
(36) Near-Infrared Light-Mediated Nanoplatforms for Cancer Thermo-Chemotherapy and Optical Imaging, Advanced Materials, 2013, 通讯作者
(37) Molecular mechanism of pancreatic tumor metastasis inhibition by Gd@C82(OH)22 and its implication for de novo design of nanomedicine, PNAS, 2012, 通讯作者
(38) Mesoporous Silica-coated Gold Nanorods as a Light-mediated Multifunctional Theranostic Platform for Cancer Treatment , Advanced Materials, 2012, 通讯作者
(39) Surface-Engineered Gold Nanorods: Promising DNA Vaccine Adjuvant for HIV-1 Treatment, Nano Letters, 2012, 通讯作者
(40) Efficient Delivery of Antitumor Drug to the Nuclei of Tumor Cells by Amphiphilic Biodegradable Poly( L-Aspartic Acid-co-Lactic Acid)/DPPE Co-Polymer Nanoparticles, Small, 2012, 通讯作者
(41) Anti-tumor activity of paclitaxel through dual-targeting carrier of cyclic RGD and transferrin conjugated hyperbranched copolymer nanoparticles, Biomaterials, 2012, 通讯作者
(42) Full Assessment of Fate and Physiological Behavior of Quantum Dots Utilizing Caenorhabditis elegans as a Model Organism, Nano Letters, 2011, 通讯作者
(43) Selective Targeting of Gold Nanorods at the Mitochondria of Cancer Cells: Implications for Cancer Therapy, Nano Letters, 2011, 通讯作者
(44) The Inhibition of Death Receptor Mediated-Apoptosis through Lysosome Stabilization following Internalization of Carboxyfullerene Nanoparticles, Biomaterials, 2011, 通讯作者
(45) Au@Pt nanostructures as oxidase and peroxidase mimetics for use in immunoassays, Biomaterials, 2011, 通讯作者
(46) Full quantification of selenium species by RP and AF-ICP-qMS with on-line isotope dilution in serum samples from mercury-exposed people supplemented with selenium-enriched yeast, Journal of Analytical Atomic Spectrometry, 2011, 通讯作者
(47) Surface chemistry and aspect ratio mediated cellular uptake of Au nanorods, Biomaterials, 2011, 通讯作者
(48) Studies on antitumor and antimetastatic activities of fullerenol in a mouse breast cancer model, Carbon, 2011, 通讯作者
(49) Significance and Systematic Analysis of Metallic Impurities of Carbon Nanotubes Produced by Different Manufacturers, Journal of Nanoscience and Nanotechnology, 2011, 通讯作者
(50) Characterization of gold nanorods in vivo by integrated analytical techniques: their uptake, retention, and chemical forms, Analytical and Bioanalytical Chemistry, 2010, 通讯作者
(51) Direct quantitative speciation of selenium in selenium-enriched yeast and yeast-based products by X-ray absorption spectroscopy, Journal of Analytical Atomic Spectrometry, 2010, 通讯作者
(52) Applications and toxicological issues surrounding nanotechnology in the food industry, Pure and Applied Chemistry, 2010, 通讯作者
(53) The effect of Gd@C82(OH)22 nanoparticles on the release of Th1/Th2 cytokines and induction of TNF-alpha mediated cellular immunity, Biomaterials, 2009, 通讯作者
(54) The scavenging of reactive oxygen species and the potential for cell protection by functionalized fullerene materials, Biomaterials, 2009, 通讯作者
(55) Fullerene derivatives protect endothelial cells against NO-induced damage, Nanotechnology, 2009, 通讯作者
(56) Fullerene nanoparticles selectively enter oxidation-damaged cerebral microvessel endothelial cells and inhibit JNK-related apoptosis, ACS Nano, 2009, 通讯作者
(2) Poly (Vinylpyrollidone) and Selenocysteine Modified Bi2Se3 Nanoparticles Enhance Radiotherapy Efficacy in Tumor and Promote Radioprotection in Normal Tissues, Advanced Materials, 2017, 通讯作者
(3) Chiral Surface of Nanoparticles Determines the Orientation of Adsorbed Transferrin and its Interaction with Receptors., ACS Nano, 2017, 通讯作者
(4) Remote Control and Modulation of Cellular Events by Plasmonic Gold Nanoparticles: Implications and Opportunities for Biomedical Applications, ACS Nano, 2017, 通讯作者
(5) Interference of Steroidogenesis by Gold Nanorod Core/Silver Shell Nanostructures: Implications for Reproductive Toxicity of Silver, Small, 2017, 通讯作者
(6) Interference of Steroidogenesis by Gold Nanorod Core/Silver Shell Nanostructures: Implications for Reproductive Toxicity of Silver, Small, 2017, 通讯作者
(7) A combined experimental and numerical study on upper airway dosimetry of inhaled nanoparticles from an electrical discharge machine shop, Particle and Fibre Toxicology, 2017, 通讯作者
(8) In vivo aggregation-induced transition between T1 and T2 relaxations of magnetic ultra-small iron oxide nanoparticles in tumor microenvironment., Nanoscale, 2017, 通讯作者
(9) Design of TPGS-functionalized Cu3BiS3 nanocrystals with strong absorption in the second near-infrared window for radiation therapy enhancement, Nanoscale, 2017, 通讯作者
(10) Light-Enhanced Antibacterial Activity of Graphene Oxide, Mainly via Accelerated Electron Transfer, Environmental Science & Technology, 2017, 通讯作者
(11) Fullerenol inhibits the cross-talk between bone marrow-derived mesenchymal stem cells and tumor cells by regulating MAPK signaling, Nanomedicine: Nanotechnology, Biology and Medicine, 2017, 通讯作者
(12) Mussel Inspired Polynorepinephrine Functionalized Electrospun Polycaprolactone Microfibers for Muscle Regeneration., Scientific Reports, 2017, 通讯作者
(13) Protein corona in vivo: dynamic complement proteins-mediated opsonization and immune modulation., Science Bulletin, 2017, 通讯作者
(14) Role of nanotechnology in HIV/AIDS vaccine development, Advanced Drug Delivery Reviews, 2016, 通讯作者
(15) Superstable Magnetic Nanoparticles in Conjugation with Near-Infrared Dye as a Multimodal Theranostic Platform, ACS Applied Materials & Interfaces, 2016, 通讯作者
(16) Rapid Degradation and High Renal Clearance of Cu3BiS3 Nanodots for Efficient Cancer Diagnosis and Photothermal Therapy in Vivo, ACS Nano, 2016, 通讯作者
(17) A Versatile Imaging and Therapeutic Platform Based on Dual-Band Luminescent Lanthanide Nanoparticles toward Tumor Metastasis Inhibition, ACS Nano, 2016, 通讯作者
(18) An experimental and computational approach to the development of ZnO nanoparticles that are safe by design, Small, 2016, 通讯作者
(19) Beyond PM2.5: The role of ultrafine particles on adverse health effects of air pollution, BBA - General Subjects, 2016, 通讯作者
(20) Silver nanoparticles induced oxidative and endoplasmic reticulum stresses in mouse tissues: implications for the development of acute toxicity after intravenous administration, Toxicology Research, 2016, 通讯作者
(21) Gold Nanomaterials in Consumer Cosmetics Nanoproducts: Analyses, Characterization and Dermal Safety Assessment, Small, 2016, 通讯作者
(22) Using Hollow Carbon Nanospheres as a Light-induced Free Radical Generator to Overcome Chemotherapy Resistance., Journal of the American Chemical Society, 2015, 通讯作者
(23) Core–Shell Upconversion Nanoparticle@Metal–Organic Framework Nanoprobes for Luminescent/Magnetic Dual-Mode Targeted Imaging, Advanced Materials, 2015, 通讯作者
(24) Use of Synchrotron Radiation-Analytical Techniques to Reveal Chemical Origin of Silver-Nanoparticle Cytotoxicity, ACS Nano, 2015, 通讯作者
(25) Bismuth Sulfide Nanorods as a Precision Nanomedicine for in Vivo Multimodal Imaging-Guided Photothermal Therapy of Tumor, ACS Nano, 2015, 通讯作者
(26) Near Infrared Laser Induced Targeted Cancer Therapy Using Thermo-Responsive Polymer Encapsulated Gold Nanorods, JACS, 2014, 通讯作者
(27) Endoplasmic Reticulum Stress Induced by Zinc Oxide Nanoparticles Is an Earlier Biomarker for Nanotoxicological Evaluation, ACS Nano, 2014, 通讯作者
(28) Novel Insights into Combating Cancer Chemotherapy Resistance Using a Plasmonic Nanocarrier: Enhancing Drug Sensitiveness and Accumulation Simultaneously with Localized Mild Photothermal Stimulus of Femtosecond Pulsed Laser, Advanced Functional Materials, 2014, 通讯作者
(29) Inhibition of Cancer Cell Migration by Gold Nanorods: Molecular Mechanisms and Implications for Cancer Therapy, Advanced Functional Materials, 2014, 通讯作者
(30) Polyhydroxylated Metallofullerenols Stimulate IL-1 Secretion of Macrophage through TLRs/MyD88/NF-κB Pathway and NLRP3 Inflammasome Activation, Small, 2014, 通讯作者
(31) Selective inhibition of breast cancer stem cells by gold nanorods mediated plasmonic hyperthermia, Biomaterials, 2014, 通讯作者
(32) Understanding the Toxicity of Carbon Nanotubes, Accounts of Chemical Research, 2013, 通讯作者
(33) Advanced nuclear analytical and related techniques for the growing challenges in nanotoxicology, Chemical Society Reviews, 2013, 第 1 作者
(34) Revealing the Binding Structure of the Protein Corona on Gold Nanorods Using Synchrotron Radiation-Based Techniques: Understanding the Reduced Damage in Cell Membranes, JACS, 2013, 通讯作者
(35) Morphologically Virus-like Fullerenol Nanoparticles Act as the Dual-functional Nanoadjuvant for HIV-1 Vaccine, Advanced Materials, 2013, 通讯作者
(36) Near-Infrared Light-Mediated Nanoplatforms for Cancer Thermo-Chemotherapy and Optical Imaging, Advanced Materials, 2013, 通讯作者
(37) Molecular mechanism of pancreatic tumor metastasis inhibition by Gd@C82(OH)22 and its implication for de novo design of nanomedicine, PNAS, 2012, 通讯作者
(38) Mesoporous Silica-coated Gold Nanorods as a Light-mediated Multifunctional Theranostic Platform for Cancer Treatment , Advanced Materials, 2012, 通讯作者
(39) Surface-Engineered Gold Nanorods: Promising DNA Vaccine Adjuvant for HIV-1 Treatment, Nano Letters, 2012, 通讯作者
(40) Efficient Delivery of Antitumor Drug to the Nuclei of Tumor Cells by Amphiphilic Biodegradable Poly( L-Aspartic Acid-co-Lactic Acid)/DPPE Co-Polymer Nanoparticles, Small, 2012, 通讯作者
(41) Anti-tumor activity of paclitaxel through dual-targeting carrier of cyclic RGD and transferrin conjugated hyperbranched copolymer nanoparticles, Biomaterials, 2012, 通讯作者
(42) Full Assessment of Fate and Physiological Behavior of Quantum Dots Utilizing Caenorhabditis elegans as a Model Organism, Nano Letters, 2011, 通讯作者
(43) Selective Targeting of Gold Nanorods at the Mitochondria of Cancer Cells: Implications for Cancer Therapy, Nano Letters, 2011, 通讯作者
(44) The Inhibition of Death Receptor Mediated-Apoptosis through Lysosome Stabilization following Internalization of Carboxyfullerene Nanoparticles, Biomaterials, 2011, 通讯作者
(45) Au@Pt nanostructures as oxidase and peroxidase mimetics for use in immunoassays, Biomaterials, 2011, 通讯作者
(46) Full quantification of selenium species by RP and AF-ICP-qMS with on-line isotope dilution in serum samples from mercury-exposed people supplemented with selenium-enriched yeast, Journal of Analytical Atomic Spectrometry, 2011, 通讯作者
(47) Surface chemistry and aspect ratio mediated cellular uptake of Au nanorods, Biomaterials, 2011, 通讯作者
(48) Studies on antitumor and antimetastatic activities of fullerenol in a mouse breast cancer model, Carbon, 2011, 通讯作者
(49) Significance and Systematic Analysis of Metallic Impurities of Carbon Nanotubes Produced by Different Manufacturers, Journal of Nanoscience and Nanotechnology, 2011, 通讯作者
(50) Characterization of gold nanorods in vivo by integrated analytical techniques: their uptake, retention, and chemical forms, Analytical and Bioanalytical Chemistry, 2010, 通讯作者
(51) Direct quantitative speciation of selenium in selenium-enriched yeast and yeast-based products by X-ray absorption spectroscopy, Journal of Analytical Atomic Spectrometry, 2010, 通讯作者
(52) Applications and toxicological issues surrounding nanotechnology in the food industry, Pure and Applied Chemistry, 2010, 通讯作者
(53) The effect of Gd@C82(OH)22 nanoparticles on the release of Th1/Th2 cytokines and induction of TNF-alpha mediated cellular immunity, Biomaterials, 2009, 通讯作者
(54) The scavenging of reactive oxygen species and the potential for cell protection by functionalized fullerene materials, Biomaterials, 2009, 通讯作者
(55) Fullerene derivatives protect endothelial cells against NO-induced damage, Nanotechnology, 2009, 通讯作者
(56) Fullerene nanoparticles selectively enter oxidation-damaged cerebral microvessel endothelial cells and inhibit JNK-related apoptosis, ACS Nano, 2009, 通讯作者
发表著作
(1) 二氧化钛纳米材料生物效应与安全应用, Biological Effets and safe application of TiO2 Nanomaterials, 科学出版社, 2010-03, 第 1 作者
(2) 先进核分析技术在金属蛋白组学与金属蛋白组学的应用, Advanced Nuclear Analytical Techniques for Metallomics and Metalloproteomics., 英国皇家化学会 RSC Publishing, 2010-03, 第 1 作者
(3) 金纳米棒的制备、性质及应用, Preparation, characteristic and application of gold nanorods, 科学出版社, 2014-03, 第 2 作者
(4) 生产与工作场所纳米颗粒暴露监测指南, 科学出版社, 2015-10, 第 1 作者
(5) Biomedical Applications and Toxicology of Carbon Nanomaterials, 德国Wiley-VCH出版社, 2016-01, 第 1 作者
(6) Chapter 45: Environment, Health and Safety Issues in Nanotechnology, in Handbook of Nanotechnology, Springer, 2017-12, 第 2 作者
(2) 先进核分析技术在金属蛋白组学与金属蛋白组学的应用, Advanced Nuclear Analytical Techniques for Metallomics and Metalloproteomics., 英国皇家化学会 RSC Publishing, 2010-03, 第 1 作者
(3) 金纳米棒的制备、性质及应用, Preparation, characteristic and application of gold nanorods, 科学出版社, 2014-03, 第 2 作者
(4) 生产与工作场所纳米颗粒暴露监测指南, 科学出版社, 2015-10, 第 1 作者
(5) Biomedical Applications and Toxicology of Carbon Nanomaterials, 德国Wiley-VCH出版社, 2016-01, 第 1 作者
(6) Chapter 45: Environment, Health and Safety Issues in Nanotechnology, in Handbook of Nanotechnology, Springer, 2017-12, 第 2 作者
科研活动
科研项目
( 1 ) 自然科学基金面上项目:金纳米棒的树枝状高分子修饰在肿瘤光热治疗中的研究, 主持, 国家级, 2011-01--2013-12
( 2 ) 自然科学基金面上项目:利用核技术研究碳纳米管的潜在神经毒理学效应, 主持, 国家级, 2010-01--2012-12
( 3 ) 欧盟第七框架计划:MARINA项目, 主持, 研究所(学校), 2011-05--2014-12
( 4 ) 973项目-课题1:工作场所中纳米颗粒的释放,职业暴露与安全性研究, 主持, 国家级, 2011-01--2015-12
( 5 ) 北京市自然科学基金面上项目:纳米银产品的表征方法以及纳米银对心血管系统安全性的研究, 主持, 省级, 2015-01--2016-12
( 6 ) 国际科技合作与交流专项:肿瘤诊疗一体化纳米药物的研制及其关键技术, 主持, 国家级, 2013-04--2016-03
( 7 ) 国家重大科学仪器设备开发专项子任务:纳米材料的细胞生物学效应与毒性评价检测平台, 主持, 国家级, 2011-10--2016-09
( 8 ) 丹麦战略研究委员会:ElectroMed项目, 主持, 研究所(学校), 2013-01--2015-12
( 9 ) 国家杰出青年科学基金:核技术及其应用, 主持, 国家级, 2015-01--2019-12
( 10 ) 大气颗粒物毒性组分与诱发机体损伤毒理学机制的研究, 主持, 国家级, 2016-01--2019-12
( 11 ) 医用及工业纳米材料的毒理学机制与安全性评价研究, 主持, 国家级, 2016-07--2021-06
( 12 ) 双模式加权成像用磁性纳米Fe3O4的应用转化研究, 主持, 部委级, 2017-12--2019-12
( 2 ) 自然科学基金面上项目:利用核技术研究碳纳米管的潜在神经毒理学效应, 主持, 国家级, 2010-01--2012-12
( 3 ) 欧盟第七框架计划:MARINA项目, 主持, 研究所(学校), 2011-05--2014-12
( 4 ) 973项目-课题1:工作场所中纳米颗粒的释放,职业暴露与安全性研究, 主持, 国家级, 2011-01--2015-12
( 5 ) 北京市自然科学基金面上项目:纳米银产品的表征方法以及纳米银对心血管系统安全性的研究, 主持, 省级, 2015-01--2016-12
( 6 ) 国际科技合作与交流专项:肿瘤诊疗一体化纳米药物的研制及其关键技术, 主持, 国家级, 2013-04--2016-03
( 7 ) 国家重大科学仪器设备开发专项子任务:纳米材料的细胞生物学效应与毒性评价检测平台, 主持, 国家级, 2011-10--2016-09
( 8 ) 丹麦战略研究委员会:ElectroMed项目, 主持, 研究所(学校), 2013-01--2015-12
( 9 ) 国家杰出青年科学基金:核技术及其应用, 主持, 国家级, 2015-01--2019-12
( 10 ) 大气颗粒物毒性组分与诱发机体损伤毒理学机制的研究, 主持, 国家级, 2016-01--2019-12
( 11 ) 医用及工业纳米材料的毒理学机制与安全性评价研究, 主持, 国家级, 2016-07--2021-06
( 12 ) 双模式加权成像用磁性纳米Fe3O4的应用转化研究, 主持, 部委级, 2017-12--2019-12
参与会议
(1)Interaction of Living Systems with Engineered Nanoparticles - Between Medical Benefit and Toxicity 2017-12-06
(2)影响纳米材料毒性的关键因素 第九届全国环境化学大会 2017-10-19
(3)金属纳米材料的代谢动力学与代谢产物的分析与表征 第八届全国毒理学会议 2017-10-16
(4)The role of advanced nuclear analytical and related techniques in nanotoxicology 2017-09-19
(5)Understanding the interaction of living systems with engineered metal nanoparticles by synchrotron radiation‐based techniques 2017-08-13
(6)Interaction of Living Systems with Engineered Nanoparticles – between Medical Benefit and Toxicity 2017-07-10
(7)Endoplasmic reticulum stress is an earlier biomarker for nanotoxicological evaluation 2016-06-01
(8)Near-infrared Light-Mediated Nanomaterials as Precision Nanomedicine 2016-02-04
(9)Endoplasmic reticulum stress is an earlier biomarker for nanotoxicological evaluation 2015-12-14
(10)Synchrotron radiation-based techniques for revealing cell trafficking and transformation of nanomaterials in biological systems 2015-09-09
(11)Application of synchrotron techniques for studying the uptake and transformation of nanomaterials in biological systems 2015-08-23
(12)Multifunctional Nanomateials for in vivo Multimodal Imaging, Photothermal and Chemotherapy 2015-07-21
(13)In Vivo Pharmacokinetic Features and Biodistribution of Engineered Gold Nanoparticles, and Their Applications in Biomedicine 2015-07-20
(2)影响纳米材料毒性的关键因素 第九届全国环境化学大会 2017-10-19
(3)金属纳米材料的代谢动力学与代谢产物的分析与表征 第八届全国毒理学会议 2017-10-16
(4)The role of advanced nuclear analytical and related techniques in nanotoxicology 2017-09-19
(5)Understanding the interaction of living systems with engineered metal nanoparticles by synchrotron radiation‐based techniques 2017-08-13
(6)Interaction of Living Systems with Engineered Nanoparticles – between Medical Benefit and Toxicity 2017-07-10
(7)Endoplasmic reticulum stress is an earlier biomarker for nanotoxicological evaluation 2016-06-01
(8)Near-infrared Light-Mediated Nanomaterials as Precision Nanomedicine 2016-02-04
(9)Endoplasmic reticulum stress is an earlier biomarker for nanotoxicological evaluation 2015-12-14
(10)Synchrotron radiation-based techniques for revealing cell trafficking and transformation of nanomaterials in biological systems 2015-09-09
(11)Application of synchrotron techniques for studying the uptake and transformation of nanomaterials in biological systems 2015-08-23
(12)Multifunctional Nanomateials for in vivo Multimodal Imaging, Photothermal and Chemotherapy 2015-07-21
(13)In Vivo Pharmacokinetic Features and Biodistribution of Engineered Gold Nanoparticles, and Their Applications in Biomedicine 2015-07-20