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中国科学院武汉病毒研究所考研导师邓菲介绍
 

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邓菲  女  博导  中国科学院武汉病毒研究所
电子邮件: df@wh.iov.cn
通信地址: 湖北省武汉市小洪山中区44号
邮政编码: 430071

 

 

 

研究领域

   

招生信息

   
招生专业
071005-微生物学
招生方向
病毒学
生物技术

教育背景

   
学历
   
学位
   

工作经历

   
工作简历
2013-08~现在, 中国科学院武汉病毒研究所, 研究员
2007-09~现在, 中国科学院武汉病毒研究所, 副研究员
2003-07~现在, 中国科学院武汉病毒研究所, 助理研究员
社会兼职
   

教授课程

   

专利与奖励

   
奖励信息
(1) 湖北省自然科学一等奖, 一等奖, 省级, 2011
专利成果
( 1 ) 一种用于检测乙型肝炎病毒的生物用品。 , 2008, 第 3 作者, 专利号: ZL 2006 1 0018346.X
( 2 ) 重组杆状病毒AcBac△cc-GP41及其构建方法 , 2011, 第 4 作者, 专利号: ZL 2007 1 0052629.0
( 3 ) 一种用于检测禽流感病毒H5N1亚型的液相芯片。, 2009, 第 4 作者, 专利号: ZL 2006 1 0018603.X
( 4 ) 高效表达SARS冠状病毒S蛋白的重组杆状病毒及构建。 , 2010, 第 3 作者, 专利号: ZL 2007 1 0052485.9
( 5 ) 用于乙型肝炎病毒共价闭合DNA的检测用品及其应用, 2012, 第 4 作者, 专利号: ZL200810197526.8
( 6 ) 用液相芯片检测呼吸道传染病病原的引物和探针及方法, 2012, 第 3 作者, 专利号: ZL201110067021.1
( 7 ) 用于杆状病毒滴度测定的重组细胞系及其测定办法, 2013, 第 1 作者, 专利号: 201310538492.5
( 8 ) 用液相芯片检测虫媒或接触传播病原的引物和探针及方法, 2013, 第 3 作者, 专利号: ZL201110067025.x
( 9 ) 一种可进行生物安全操作的冷冻干燥装置, 2017, 第 2 作者, 专利号: ZL201721487074.8

出版信息

   
发表论文
(1) Detection and characterization of a novel hepacivirus in long-tailed ground squirrels (Spermophilus undulatus) in China., Arch Virol., 2019, 第 11 作者
(2) Improving Baculovirus Transduction of Mammalian Cells by Incorporation of Thogotovirus Glycoproteins, Virol Sin., 2019, 第 3 作者
(3) Interferon-γ-Directed Inhibition of a Novel High-Pathogenic Phlebovirus and Viral Antagonism of the Antiviral Signaling by Targeting STAT1., Front Immunol., 2019, 第 9 作者
(4) Zika virus circumvents host innate immunity by targeting the adaptor proteins MAVS and MITA, FASEB J., 2019, 第 9 作者
(5) The major hurdle for effective baculovirus transduction into mammalian cells is passing early endosomes., J Virol., 2019, 第 4 作者
(6) Taxonomy of the order Bunyavirales: update 2019., Arch Virol., 2019, 第 12 作者
(7) Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1., J Biol Chem., 2019, 第 2 作者
(8) Quantitative Proteomic Analysis Reveals Unfolded-Protein Response Involved in Severe Fever with Thrombocytopenia Syndrome Virus Infection., J Virol., 2019, 第 7 作者
(9) Single dose of a rVSV-based vaccine elicits complete protection against severe fever with thrombocytopenia syndrome virus., NPJ Vaccines., 2019, 第 12 作者
(10) Baculovirus Per Os Infectivity Factor Complex: Components and Assembly., J Virol., 2019, 第 12 作者
(11) Single-Particle Tracking Reveals the Sequential Entry Process of the Bunyavirus Severe Fever with Thrombocytopenia Syndrome Virus., Small., 2019, 第 5 作者
(12) Identification and genomic sequence analysis of a new Spodoptera exigua multiple nucleopolyhedrovirus, SeMNPV-QD, isolated from Qingdao, China., J Invertebr Pathol., 2019, 第 5 作者
(13) N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication., Nucleic Acids Res., 2019, 第 11 作者
(14) The group I alphabaculovirus-specific protein, AC5, is a novel component of the occlusion body but is not associated with ODVs or the PIF complex., J Gen Virol., 2018, 第 5 作者
(15) Isolation, Characterization, and Phylogenetic Analysis of Two New Crimean-Congo Hemorrhagic Fever Virus Strains from the Northern Region of Xinjiang Province, China., Virol Sin., 2018, 第 11 作者
(16) Fine mapping epitope on glycoprotein-Gn from Crimean-Congo hemorrhagic fever virus., Comp Immunol Microbiol Infect Dis., 2018, 第 11 作者
(17) Mapping of B-cell epitopes on the N- terminal and C-terminal segment of nucleocapsid protein from Crimean-Congo hemorrhagic fever virus., PLoS One., 2018, 第 11 作者
(18) Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group I of Alphabaculovirus., Virol Sin., 2018, 第 12 作者
(19) Establishment of Baculovirus-Expressed VLPs Induced Syncytial Formation Assay for Flavivirus Antiviral Screening., Viruses., 2018, 第 11 作者
(20) Zika Virus Baculovirus-Expressed Virus-Like Particles Induce Neutralizing Antibodies in Mice., Virol Sin., 2018, 第 11 作者
(21) Development of Multi-analyte Suspension Assay for Simultaneously Efficient Detection of Avian Influenza Virus A Subtypes., Virol Sin., 2018, 第 5 作者
(22) The functional oligomeric state of tegument protein GP41 is essential for baculovirus BV and ODV assembly., J Virol., 2018, 第 4 作者
(23) HearNPV Pseudotyped with PIF1, 2, and 3 from MabrNPV: Infectivity and Complex Stability., Virol Sin., 2018, 第 7 作者
(24) Prevalence and Phylogenetic Analysis of Crimean-Congo Hemorrhagic Fever Virus in Ticks from Different Ecosystems in Xinjiang, China., Virol Sin., 2018, 第 11 作者
(25) A novel tick-borne phlebovirus, closely related to severe fever with thrombocytopenia syndrome virus and Heartland virus, is a potential pathogen., Emerg Microbes Infect., 2018, 第 11 作者
(26) Tick-Borne Viruses., Virol Sin., 2018, 第 11 作者
(27) Genome analysis of a novel Group I alphabaculovirus obtained from Oxyplax ochracea., PLoS One., 2018, 第 8 作者
(28) A novel glycoprotein D-specific monoclonal antibody neutralizes herpes simplex virus., Antiviral Res., 2017, 第 8 作者
(29) A new strain of Crimean-Congo hemorrhagic fever virus isolated from Xinjiang, China., Virol Sin., 2017, 第 11 作者
(30) Three conserved regions in baculovirus sulfhydryl oxidase, P33, are critical for enzymatic activity and function., J Virol., 2017, 第 5 作者
(31) Detection, isolation, and characterization of chikungunya viruses associated with the Pakistan outbreak of 2016-2017., Virol Sin., 2017, 第 9 作者
(32) Antigenicity of severe fever with thrombocytopenia syndrome virus nucleocapsid protein and its potential application in the virus serodiagnosis., Virol Sin., 2017, 第 11 作者
(33) The roles of ebolavirus glycoproteins in viral pathogenesis., Virol Sin., 2017, 第 2 作者
(34) Heartland virus NSs protein disrupts host defenses by blocking the TBK1 kinase-IRF3 transcription factor interaction and signaling required for interferon induction., J Biol Chem., 2017, 第 4 作者
(35) Ebola virus mucin-like glycoprotein (Emuc) induces remarkable acute inflammation and tissue injury: evidence for Emuc pathogenicity in vivo., Protein Cell., 2017, 第 8 作者
(36) Construction and Rescue of a Functional Synthetic Baculovirus., ACS Synth Biol., 2017, 第 11 作者
(37) Extensive evolution analysis of the global chikungunya virus strains revealed the origination of CHIKV epidemics in Pakistan in 2016., Virol Sin., 2017, 第 11 作者
(38) Quantitative Proteomic Analysis of Mosquito C6/36 Cells Reveals Host Proteins Involved in Zika Virus Infection., J Virol., 2017, 第 7 作者
(39) Isolation, characterization, and phylogenic analysis of three new severe fever with thrombocytopenia syndrome bunyavirus strains derived from Hubei Province, China., Virol Sin., 2017, 第 10 作者
(40) Characterization of the viral fibroblast growth factor homolog of Helicoverpa armigera single nucleopolyhedrovirus., Virol Sin., 2016, 第 6 作者
(41) Pathologic Studies of Fatal Encephalomyelitis in Children Caused by Enterovirus 71, Am J Clin Pathol., 2016, 第 10 作者
(42) Spatial Analysis of Severe Fever with Thrombocytopenia Syndrome Virus in China Using a Geographically Weighted Logistic Regression Model., Int J Environ Res Public Health., 2016, 第 2 作者
(43) Molecular basis for the formation of ribonucleoprotein complex of Crimean-Congo hemorrhagic fever virus., Journal of Structural Biology., 2016, 第 11 作者
(44) Genome Sequencing and Analysis of Catopsilia pomona nucleopolyhedrovirus: A Distinct Species in Group I Alphabaculovirus., PLoS One., 2016, 第 9 作者
(45) The Host Specificities of Baculovirus per os Infectivity Factors., PLoS One., 2016, 第 6 作者
(46) Migration, recombination, and reassortment are involved in the evolution of severe fever with thrombocytopenia syndrome bunyavirus., Infect Genet Evol., 2016, 第 9 作者
(47) Mutational and functional analysis of N-linked glycosylation of envelope fusion protein F of Helicoverpa armigera nucleopolyhedrovirus., J Gen Virol., 2016, 第 11 作者
(48) Phylogenetic analysis revealed the central roles of two African countries in the evolution and worldwide spread of Zika virus., Virol Sin., 2016, 第 11 作者
(49) A 3-year follow-up study of the seroprevalence of antibodies to avian influenza A H5, H6, H7 and H10 viruses among the general population of Wuhan, China., J Clin Virol., 2016, 第 11 作者
(50) Virus like particle-based vaccines against emerging infectious disease viruses., Virol Sin., 2016, 第 11 作者
(51) P33 of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus is a functional homolog of AcP33., Virol Sin., 2016, 第 5 作者
(52) Characterization of two monoclonal antibodies, 38F10 and 44D11, against the major envelope fusion protein of Helicoverpa armigera nucleopolyhedrovirus., Virol Sin., 2016, 第 3 作者
(53) Glycoprotein E of the Japanese Encephalitis Virus forms virus-like particles and induces Syncytia when expressed by a baculovirus. , J Gen Virol. , 2015, 第 11 作者
(54) The FP25K Acts as a Negative Factor for the Infectivity of AcMNPVBudded Virus., PLoS One., 2015, 第 11 作者
(55) 杆状病毒病毒粒子结构与口服感染和系统感染的关系., Chin Sci Bull., 2015, 第 3 作者
(56) An in vitro recombination-based reverse genetic system for rapid mutagenesis of structural genes of the Japanese encephalitis virus., Virol Sin., 2015, 第 11 作者
(57) Genomic Sequencing and Analysis of Sucra jujuba Nucleopolyhedrovirus., Plos One, 2014, 第 11 作者
(58) The ha72 Core Gene of Baculovirus Is Essential for Budded Virus Production and Occlusion-Derived Virus Embedding, and Amino Acid K22 Plays an Important Role in Its Function., J Virol. , 2014, 第 3 作者
(59) Identification and functional analysis of inter-subunit disulfide bonds of F protein of HearNPV. , J Gen Virol. , 2014, 第 4 作者
(60) Fine epitope mapping of the central immunodominant region of nucleoprotein from Crimean-Congo Hemorrhagic Fever Virus (CCHFV). , Plos One, 2014, 第 4 作者
(61) Unraveling the Entry Mechanism of Baculoviruses and Its Evolutionary Implications.,  J Virol . , 2014, 第 11 作者
(62) Serological study of antibodies to influenza A viruses among general population in Wuhan city China., J Clinic Virol. , 2014, 第 11 作者
(63) Characterization and Genomic Analysis of a Plaque Purified Strain of Cyanophage PP., Virologica Sinica., 2013, 第 11 作者
(64) Freshwater Cyanophages., Virologica Sinica. , 2013, 第 3 作者
(65) The ha72 core gene of baculovirus is essential for budded virus production and Occlusion-Derived Virus embedding, and amino acid K22 plays an important role in its function. , J Virol., 2013, 第 3 作者
(66) Reassortment and migration analysis of Crimean–Congo haemorrhagic fever virus., J Gen Virol. , 2013, 第 2 作者
(67) Comparative Proteomics Reveal Fundamental Structural and Functional Differences between the Two Progeny Phenotypes of a Baculovirus., J Virol., 2013, 第 3 作者
(68)  Betabaculovirus F Proteins Showed Different Efficiency when Rescuing the , Virology., 2013, 第 4 作者
(69) ORF85 of HearNPV encodes the per os infectivity factor 4 (PIF4) and is essential for the formation of the PIF complex.2012. , Virology., 2012, 第 3 作者
(70) Functional studies of per os infectivity factor 3 of Helicoverpa armigera nucleopolyhedrovirus., J Gen Virol. , 2012, 第 11 作者
(71)  Incorporation of GP64 into Helicoverpa armigera nucleopolyhedrovirus enhances virus infectivity in vivo and in vitro., J Gen Virol. , 2012, 第 11 作者
(72) Analysis of the structural proteins from the Musca domestica hytrosavirus with an emphasis on the major envelope protein., Journal of Invertebrate Pathology., 2012, 第 2 作者
(73) Helicoverpa armigera nucleopolyhedrovirusocclusion-derived virus-associated protein, HA100,affects oral infectivity in vivo but not virus replicationin vitro, Journal of General Virology, 2011, 第 11 作者
(74) Partial Functional Rescue of HearNPV Infectivity by Substitution of F Protein with GP64 from AcMNPV. , Journal of Virology, 2010, 第 11 作者
(75) Proteomics of the Autographa californica Nucleopolyhedrovirus Budded Virions.,  Journal of Virology, 2010, 第 2 作者
(76) Identification of protein–protein interactions of the occlusion-derived virus-associated proteins of Helicoverpa armigera nucleopolyhedrovirus. , Journal of General Virology, 2010, 第 3 作者
(77) AcMNPV efficiently infects Sf9 cells and transduces mammalian cells via direct fusion with the plasma membrane at low pH., Journal of Virology, 2010, 第 4 作者
(78) The F protein of Helicoverpa armigera single nucleopolyhedrovirus can be substituted functionally with its homologue from Spodoptera exigua multiple nuclopolyhedrovirus. , Journal of General Virology, 2009, 第 4 作者
(79) Angiotensin-converting enzyme 2 (ACE2) from raccoon dog can serve as an efficient receptor for the spike protein of severe acute respiratory syndrome coronavirus., Journal of General Virology, 2009, 第 11 作者

 

 


 

 

 

 
 
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