Surface Plasmon Resonance; Impedance sensor；Biosensors ；Ce​ll based biosensor

   

080300-光学工程
083100-生物医学工程
0809Z1-生物电子学

阻抗传感器,微机电系统,生医传感器,细胞传感器
 

 

2018/04 - 至今 
University of Chinese Academy of Science， 
光电学院，副教授  

 

2012/07 - 2018/04 
University of Chinese Academy of Science，
电子电气与通信工程学院，副教授

2010-2012
Postdoctoral Research in
Electrical Engineering, Nnational Central University, Taiwan
Major study in” Impedance sensor and PZT sensor development” 

2010-2011
Short-term visiting researcher in Tokyo Tech’s
Department of Metallurgy and Ceramics Science 

2010-2010
Collaborative part-time researcher in diabetes research program 
with New Business Programs, Biomedical Research Laboratories
Delta Electronics, INC., Taiwan. 

2004-2005 
Assistant researcher in Bioscience and Biotechnology Center, 
National Cheng Kung University, Taiwan

 

生医光电系统在臨床上的应用
生物光电实验
生物医学工程
生物医学工程特论
生医工程特论
纳米科学技术概论

教学目的、要求
生医工程是一门跨领域(inter-discipline)的学科，透过本课程的介绍，将可以初步了解在医学上各种运用工程科学的理论与技术，以及如何解决在人体结构(structure)、功能(functionality)中医学临床上之相关问题。
参考教材
相关国外期刊文献生物医学工程文献资料
主要内容
第1章 生物医学工程应用与发展 第2章 电生理学 第3章 生医传感器 第4章 生医仪表 第5章 生物力学 第6章 辐射医学影像 第7章 生医光学 第8章 生医材料 第9章 组织再生 第10章 纳米生医科技

   

（1） 国科大创新创业大赛 分赛一等奖, 研究所（学校）, 2018
（2） 国科大创新创业大赛 总结赛三等奖, 研究所（学校）, 2018
（3） 博士论文优等奖指导奖, 其他, 2016

（ 1 ） 平衡枕, 实用新型, 2013, 第 1 作者, 专利号: ZL2012 2 0197453.4
（ 2 ） 糖化血红素检测, 发明, 2015, 第 2 作者, 专利号: 台湾发明专利第I 472755号
（ 3 ） 一种用于生化分析的纸基电极检测平台及其制备方法, 发明, 2016, 第 3 作者, 专利号: 201610285084.7
（ 4 ） 种基于生物相容性材料的柔性电极及其制备方法和应用, 发明, 2016, 第 4 作者, 专利号: 20161100324.7
（ 5 ） 一种具有低电子转移阻抗的导电碳材料的制备方法, 发明, 2017, 第 3 作者, 专利号: 201710540576.0
（ 6 ） 一种利用电阻法检测空气颗粒物的方法, 发明, 2017, 第 5 作者, 专利号: 2017104042312
（ 7 ） 一种可连续旋转的光学扫描装置, 发明, 2017, 第 2 作者, 专利号: 201711067233.3
（ 8 ） 一种可连续旋转的光学扫描装置, 发明, 2018, 第 2 作者, 专利号: 201810033209.6）

   

（1） 一种低成本的表面等离子体共振检测系统, 仪表技术与传感器, 2018, 通讯作者
（2） High sensitivity glycated hemoglobin (HbA1c) aptasensor inrapid prototyping surface plasmon resonance, Sensors And Actuators B: Chemical, 2018, 通讯作者
（3） Angle scanning surface plasmon resonance system with 3D printed components for bio recognition investigation, Soft Matter Photonics, 2018, 通讯作者
（4） Development of carbon
graphene-based aptamer biosensor for EN2, Analytical Biochemistry, 2017, 第 3 作者
（5） Ultra-low charge transfer resistance carbons by one-pot+hydrothermal method for glucose sensing, SCIENCE CHINA Materials, 2017, 通讯作者
（6） Analytical performance of paper electro-biosensor detection platform for point-of-care diagnosis, Cellulose, 2016, 通讯作者
（7） Screen-printed carbon electrode-based electrochemical immunosensor for rapid detection of microalbuminuria, Biosensors and Bioelectronics, 2016, 通讯作者
（8） Impedance sensor for rapid enumeration of E. coli in milk samples, Electrochimica Acta, 2015, 通讯作者
（9） CAPACITANCE SENSOR FOR DETECTING ESCHERICHIA COLI IN URINARY, Journal of Microbiology, Immunology and Infection, 2015, 第 2 作者
（10） Detecting human serum albumin using screen-printed carbon electrode by cyclic voltammetry, Journal of Microbiology, Immunology and Infection, 2015, 第 2 作者
（11） Impedimetric method for measuring ultra-low E. coli concentrations in human urine, Biosensors and Bioelectronics, 2015, 通讯作者
（12） Resonant efficiency improvement design of piezoelectric biosensor for bacteria gravimetric sensing, Bio-Medical Materials and Engineering, 2014, 通讯作者
（13） Electrochemical simulation of L929 cells attached on micro scale electrodes, 24th Anniversary World Congress on Biosensors, 2014, 第 3 作者
（14） Cyclic Voltammetry Characteristics of the Portable Electrochemical System in Comparison with IM6ex Workstation, International Symposium on Chemical-Environmental-Biomedical Technology, 2014, 第 2 作者
（15） Optimization of stearic acid modified porous carbon electrode for HSA detection, International Symposium on Chemical-Environmental-Biomedical Technology, 2014, 通讯作者
（16） Developmental and reproductive toxicant detection using impedance sensor, 24th Anniversary World Congress on Biosensors, 2014, 第 2 作者
（17） Concept for E.coli detection using interdigitatedmicroelectrode impedance sensor, Engineering in Medicine and Biology Society (EMBC), 35th Annual International Conference of the IEEE, 2013, 第 2 作者
（18） Interdigitated microelectrode impedance sensor design for, The 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2013, 第 2 作者
（19） Preparation and Evaluation of Gelatin as a Screen Printing Substrate, The 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2013, 第 2 作者
（20） Monitoring Inflammation of RAW264.7 Using Screen-Printing Interdigitated Electrodes by Electrochemical Impedance Spectroscopy, The 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2013, 第 2 作者
（21） Simulation of Impedance Changes Due to Cell Attached at Micro Scale Electrode, The 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2013, 第 3 作者
（22） Impedance-based analysis of mouse L929 cells growth was using a novel portable detection system, Journal of the Taiwan Institute of Chemical Engineers, 2012, 第 1 作者
（23） Interdigitated microelectrode-based impedance sensors for E-coli detection, International Conference of Exhibition on Biosensors and Bioelectronics, 2012, 第 1 作者
（24） Preparation and Characteristics of Screen-printing Electrode of Chitosan, International Conference of Exhibition on Biosensors and Bioelectronics , 2012, 第 3 作者
（25） The Study of Gelatin as an Electrode Substrate for Biosensor System, International Conference of Exhibition on Biosensors and Bioelectronics , 2012, 第 4 作者
（26） Screen-printed electrode design for cell behaviors detection by electrical cell-substrate impedance sensing, International Conference of Exhibition on Biosensors and Bioelectronics , 2012, 第 2 作者
（27） Portable Bio-impedance Detection System Developmen, International Conference of Exhibition on Biosensors and Bioelectronics , 2012, 第 2 作者
（28） Development of a portable impedance detection system for monitoring the growth of mouse L929 cells, Journal of the Taiwan Institute of Chemical Engineers, 2012, 第 1 作者
（29） A capacitance sensor system for oligonucleotide hybridization detection, SENSORS AND MATERIALS, 2011, 第 2 作者
（30） Surface plasmon resonance biosensor with high anti-fouling ability for the detection of cardiac marker troponin T, ANALYTICA CHIMICA ACTA, 2011, 通讯作者
（31） Development of a capacitance measurement system for human serum albumin detection, electronics letter, 2010, 通讯作者
（32） Simulation of Interdigitated Electrodes for Sensing Different Dielectric Materials, Annual Symposium of Biomedical Engineering, 2010, 第 1 作者
（33） Simulation on Spiral Inductor with Different Dielectric Materials, Annual Symposium of Biomedical Engineering , 2010, 第 1 作者
（34） Interdigitated Microelectrode Impedance Sensor for Water Quality Testing of Escherichia coli (E. coli) in Suspensions, Annual Symposium of Biomedical Engineering , 2010, 第 1 作者
（35） The Research of Impedimetric Characteristic Simulation Applied in the Different Geometry Biosensor, Annual Symposium of Biomedical Engineering , 2010, 第 1 作者
（36） Self-made Screen-printed Electrode Used for Detection of HSA by AC Impedance Spectroscopy, Annual Symposium of Biomedical Engineering , 2010, 第 1 作者
（37） Detection of Hemoglobin by AC Impedance Analysis, 2010 Annual Symposium of Biomedical Engineering, Annual Symposium of Biomedical Engineering , 2010, 第 1 作者
（38） Development of a capacitance measurement system for human serum albumin detection, Electronics letters, 2010, 通讯作者
（39） A capacitance sensor system for oligonucleotide hybridization detection, SENSORS AND MATERIALS, 2010, 第 2 作者
（40） A New PZT Piezoelectric Sensor for Gravimetric Applications Using the Resonance-Frequency Detection, Sensors and Actuators B, 2009, 第 2 作者
（41） The Research of Impedimetric Biosensors for Human Serum Albumin Detection, AsiaSense 2009 (The 4th International Conference on Sensors) , 2009, 第 1 作者
（42） Impedance Analysis of Metabolism and Proliferation of Mouse Fibroblast Cells L929 by a Portable Interdigitated Microelectrodes Detection System, AsiaSense 2009 (The 4th International Conference on Sensors) , 2009, 第 3 作者
（43） Development of PZT Piezoelectric Sensor for Microbalance Application, AsiaSense 2009 (The 4th International Conference on Sensors), 2009, 第 3 作者
（44） A New PZT Piezoelectric Sensor for Gravimetric Applications Using the Resonance-Frequency Detection, Sensors and Actuators B, 2009, 第 2 作者
（45） The surface modification of silver nanoparticles by phosphoryl disulfides for improved biocompatibility and intracellular uptake, Biomaterials, 2008, 第 3 作者
（46） Characterization of PZT Thin Films by Sol-Gel Method in Application of Resonant Sensor, The 2nd International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2008) , 2008, 第 2 作者
（47） Fabrication of piezoelectric sensors based on PZT thin films for protein detection,  The Tenth World Congress on Biosensors, 2008, 第 2 作者
（48） Development of impedance sensors for label-free human serum albumin detection, The Tenth World Congress on Biosensors , 2008, 第 2 作者
（49） The surface modification of silver nanoparticles by phosphoryl disulfides for improved biocompatibility and intracellular uptake, Biomaterials, 2008, 第 3 作者
（50） The Development of Oligonucleotide Micro Array Detecting Sytem , International Conference on on Solid State Devices and Materials, 2007, 第 2 作者
（51） Preparation of PZT Thin Film for Infrared Sensing Application, Biomedical Engineering Society 2006 Annual Symposium, 2006, 第 2 作者
（52） The Development of Microarray-based Oligonucleotide Detecting System, , Biomedical Engineering Society 2006 Annual Symposium, 2006, 第 2 作者
（53） Characterization of PZT Thin Films by Sol-gel Method in pplication of Resonant Sensor, Electron Devices and Materials Symposia (IEDMS), 2006, 第 3 作者
（54） Processing of PZT pyroelectric thin film for infrared sensor, International Electron Devices andMaterials Symposia (IEDMS), 2006, 第 3 作者
（55） The Detection of the Protein Mass by PZT Piezoelectric Sensor, Young Asian Biochemical Engineer Community, 2006, 第 3 作者
（56） Preparation the Impedance sensor Array Detection DNA Hybridization with Au Nanoparticale enhanced, Young Asian Biochemical Engineer Community, 2006, 第 2 作者
（57） Optimization of Immobilization and Hybridization Efficiency of Single-Strand DNA on Micro-Electrode Biochips, Biomedical Engineering Society Annual Symposium, 2005, 通讯作者
（58） Phosphorylcholine-protected Nanoparticles Functionalized wuth Both Magnetic and Potoluminescent Properties, NSTI Bio Nano Conference and Trade Show, 2005, 第 2 作者
（59） Biocompatible Silver Nanoparticles Protected by Phosphorylcholine-Ended Disulfides, 7th World Biomaterials Congress, 2004, 第 3 作者
（60） Preparation and characterization of biocompatible nanoparticles with magnetic and photoluminescent properties, 7th World Biomaterials Congress, 2004, 第 2 作者
（61） Evaluating Chitosan/β-tricalcium phosphate Microspheres as a constituent to PMMA, 7th World Biomaterials Congress, 2004, 通讯作者
（62） Evaluating Chitosan/Tricalcium Phosphate/PMMA Cement Composites as Bone Repairing Materials, Journal of Applied Polymer Science, 2003, 第 4 作者
（63） HonApplications of superparamagnetic nanoparticles on pattern fabrication and modification, International symposium on nano science and technology, 2003, 第 3 作者
（64） Evaluating Chitosan/Tricalcium Phosphate/PMMA Cement Composites as Bone Repairing Materials, Journal of Applied Polymer Science, 2003, 第 4 作者
（65） Studies of Injectable Chitosan/TCP/PMMA Composites as Bone Repairing Materials, IUPAC world Polymer Congress , 2002, 第 2 作者
（66） 

陳靖容，Development of impedimetric and piezoelectric sensing technology for biomedical applications，Electrical Engineering, Nnational Central University, Taiwan, 2010/7 博士学位论文

1.      Yu Xiang Zhou, Ching Jung Chen, Jen Tsai Liu, Shwu Jen Chang, Development of Multi-wall Carbon Nanotube Modified Interdigitated Electrodes as C-Reactive Protein Biosensors, Asia Pacific Conference on Life Science and Biological Engineering, 2018 March 27-29

2.      Jiaxin Che, Yu-Xiang Zhou, Ching-Jung Chen, Jen-Tsai Liu and Shwu Jen Chang, THE STUDY OF REVERSE IONTOPHORESIS DEVICE COMBINATION WITH GLUCOSE ELECTROCHEMICAL DETECTION, 2017.11.17-18

3.      颜靖书, 陈靖容, 趙湛,郭秀花,刘仁材, 电渗透无创血糖电化学生物传感器, 中国生物医学工程大会, 2017.04.20-22

4.      X.X. HE, C.S. YEN, J.T. LIU, C.J. CHEN, A Screen-printed Flexible Carbon Electrode with PDMS (polydimethylsiloxane) as Substrate, The Fifth International Multi-Conference on Engineering and Technology Innovation (IMETI),2016.10.28-11.01, Taichung, Taiwan. (分会报告)

5.      B.T. HU, C.S.YEN, J.T. LIU, C.J. CHEN, N, S-doped hydrothermal carbons derived from L-cysteine and glucose for biosensor applications, The sixth Collaborative Conference on 3D & Materials Research (CC3DMR), 2016.06.20-06.24, Incheon, South Korea. (分会报告)

6.      Ching-Shu Yen, ChangBing Tao, Jen-Tsai Liu, Ching-Jung Chen, Inkjet printing technology for low-cost paper-based electrochemical biosensor, 26th Anniversary World Congress on Biosensors, 2016.05.25-05.27, Cothenburg, Sweden. (分会报告)

7.      Chang-Bing Tao, Ching-Shu Yen, Shu-Ying Chen, Shwu-Jen Chang, Jen-Tsai Liu, Ching-Jung Chen. Paper-based electrochemical biosensor for glucose detection, The 4th International Academic Conference on Development in Science and Technology (IACDST-2015), October 29, 2015, Beijing, China.

8.      Chen-guang Zhan, Ching-Shu Yen, Shu-Ying Chen, Shwu-Jen Chang, Jen-Tsai Liu, Ching-Jung Chen, Low Cost Surface Plasmon Resnance, The 4th International Academic Conference on Development in Science and Technology (IACDST-2015), October 29, 2015, Beijing, China.

9.      Jen-Tsai Liu, Chang-Bing Tao, Ching-Jung Chen, Zhongbo Hu, Chen Guang Zhang, BoTao Hu, Paper-based electrochemical biosensor detection platform. International Conference on Nanomedicine and NanoBiotechnology (ChinaNanomedicine 2015) April 6-9, 2015, Hangzhou, China.

10.   Y.F. Lin, S. Kalpana, J.T. Liu, C.J. Chen, J.Z. Tsai, Optimization of stearic acid modified porous carbon electrode for HSA detection, 2014 International Symposium on Chemical-Environmental-Biomedical Technology, September 10-14, Taoyuan, Taiwan.

11.   S.Y. Lai, C.J. Chen, J.T. Liu, S. Kalpana, J.Z. Tsai, Cyclic Voltammetry Characteristics of the Portable Electrochemical System in Comparison with IM6ex Workstation, 2014 International Symposium on Chemical-Environmental-Biomedical Technology, September 10-14, Taoyuan, Taiwan.

12.   Kalpana, C-J. Chen, J-T. Liu, J-Z. Tsai，Developmental and reproductive toxicant detection using impedance sensor，24th Anniversary World Congress on Biosensors 2014，2014.5.27-2014.5.30。

13.   Y.F. Lin, S. Kalpana, J.T. Liu, C.J. Chen, J.Z，Optimization of stearic acid modified porous carbon electrode for HSA detection，2014 International Symposium on Chemical-Environmental-Biomedical Technology，2014.9.10-2014.9.14。

14.   S.Y. Lai, C.J. Chen, J.T. Liu, S. Kalpana, J.Z，Cyclic Voltammetry Characteristics of the Portable Electrochemical System in Comparison with IM6ex Workstation，2014 International Symposium on Chemical-Environmental-Biomedical Technology，2014.9.10-2014.9.14。

15.   Y.I. Huang, J.T. Liu, C.J. Chen, J.Z. Tsai, S.，Electrochemical simulation of L929 cells attached on micro scale electrodes，24th Anniversary World Congress on Biosensors 2014，2014.5.27-2014.5.30。

16.   Ching-Shu Yen, Ching-Jung Chen, Jen-Tsai Liu,，Preparation and Evaluation of Gelatin as a Screen Printing Substrate，35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC2013)，2013.7。

17.   Kuan Yao Wang, Ching-Jung Chen, Jen-Tsai Liu,，Monitoring Inflammation of RAW264.7 Using Screen-Printing Interdigitated Electrodes by Electrochemical Impedance Spectroscopy，The 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC’13)，2013.7。

18.   Yi-Shan Huang, Jen-Tsai Liu, Ching-Jung Chen,，Simulation of Impedance Changes Due to Cell Attached at Micro Scale Electrode，The 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC’13)，2013.7。

19.     C.J. Chen*, J.Z. Tsai, S. Kalpana, J.T. Liu，Interdigitated microelectrode-based impedance sensors for E-coli detection，Biosensors & Bioelectronics 2012，2012.5.14-2012.5.16。

20.   S.J. Chang, C.S. Yen, C.J. Chen, J.T. Liu,，Preparation and Characteristics of Screen-printing Electrode of Chitosanm，Biosensors & Bioelectronics 2012，2012.5.14-2012.5.16。

21.   M.W. Lee, C.S. Yen, J.T. Liu, C.J. Chen,，The Study of Gelatin as an Electrode Substrate for Biosensor System，Biosensors & Bioelectronics 2012，2012.5.14-2012.5.16。

22.   J.Z. Tsai, C.J. Chen, Y.J. Lin*, J.T. Liu，Screen-printed electrode design for cell behaviors detection by electrical cell-substrate impedance sensing，Biosensors & Bioelectronics 2012，2012.5.14-2012.5.16。

23.   J.Z. Tsai, C.J. Chen, Y.J. Lin*, J.T. Liu，Portable Bio-impedance Detection System Development，Biosensors & Bioelectronics 2012，2012.5.14-2012.5.16。

24.   Ching-Jung Chen, Kang-Jong Peng, Jen-Tsai Liu，Simulation of Interdigitated Electrodes for Sensing Different Dielectric Materials，2010 Annual Symposium of Biomedical Engineering，2010.12.10-2010.12.11。

25.   Ching-Jung Chen, Tsung-Chen Fu, Jen-Tsai Liu,，Simulation on Spiral Inductor with Different Dielectric Materials，2010 Annual Symposium of Biomedical Engineering，2010.12.10-2012.12.11。

26.   Ching-Jung Chen, Settu Kalpana, Jang-Zern Tsa，Interdigitated Microelectrode Impedance Sensor for Water Quality Testing of Escherichia coli (E. coli) in Suspensions，2010 Annual Symposium of Biomedical Engineering，2010.12.10-2012.12.11。

27.   Ching-Jung Chen, Chih-Chung Chiu, Jen-Tsai Li，The Research of Impedimetric Characteristic Simulation Applied in the Different Geometry Biosensor，2010 Annual Symposium of Biomedical Engineering，2010.12.10-2012.12.11。

28.    Ching-Jung Chen, Yu-Min Chen, Jen-Tsai Liu, H，Self-made Screen-printed Electrode Used for Detection of HSA by AC Impedance Spectroscopy，2010 Annual Symposium of Biomedical Engineering，2010.12.10-2010.12.11。

29.   Ching-Jung Chen, Yong-Nian Wei, Wen-Yih Chen, Jen，Detection of Hemoglobin by AC Impedance Analysis，2010 Annual Symposium of BME，2010.12.10-2010.12.11

 

   

1. 台湾国立中央大学,电机工程学系, 蔡章仁,电生医实验室
2. 台湾私立义守大学,生物医学工程学系, 张淑真 郭士民, 生医材料实验室

   

 

中国科学院大学 电子电气与通信工程学院 张晨光 已毕业
中国科学院大学 电子电气与通信工程学院 和欣欣 已毕业

中国科学院大学 电子电气与通信工程学院 车佳欣 已毕业
中国科学院大学 电子电气与通信工程学院 孙大鹏

中国科学院大学 电子电气与通信工程学院 周玉龙

 

 

中国科学院大学 材料科学与光电技术学院 刘浩然
中国科学院大学 材料科学与光电技术学院 朱桂贤
中国科学院大学 材料科学与光电技术学院 郑晓鹏
中国科学院大学 材料科学与光电技术学院 陶常冰
中国科学院大学 材料科学与光电技术学院 胡博韬

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