2007-09--2009-05 University of Connecticut 工商管理硕士(MBA)
2004-09--2009-02 University of Connecticut 博士
2000-09--2003-06 中科院上海药物研究所 硕士
1996-09--2000-06 兰州大学 学士
学历
学位
工作经历
工作简历
2016-05~现在, 中国科学院上海生命科学研究院生物化学与细胞生物学研究所, 中国科学院特聘研究员
2011-01~现在, 中国科学院生物化学与细胞生物学研究所, 二级研究员
2010-05~2011-01,University of Connecticut Health Center, Assistant Professor
2009-04~2010-04,University of Connecticut Health Center, 博士后
2007-09~2009-05,University of Connecticut, 工商管理硕士(MBA)
2004-09~2009-02,University of Connecticut, 博士
2000-09~2003-06,中科院上海药物研究所, 硕士
1996-09~2000-06,兰州大学, 学士
社会兼职
2018-01-01-今,Mobile DNA, 编委
2017-07-01-2022-06-30,Journal of Biological Chemistry, 编委
2017-05-31-今,HGNC基因命名委员会, 委员
2016-08-01-今,Chinese Biological Investigators Society, 理事
2015-09-01-今,外籍评委, European Research Council Advanced Grant
2015-05-01-今,Trends in Genetics, 编委
2015-01-01-今,上海科技大学, 特聘教授
2014-06-01-今,Genome Biology, 编委
2011-04-01-今,康涅狄格大学健康中心客座教授, 客座教授
2011-01-01-今,Frontiers in Non-Coding RNA, 编委
(1) N6-Methyladenosines Modulate A-to-I RNA Editing, Mol Cell, 2018, 第 11 作者
(2) RNA-binding protein SAMD4 regulates skeleton development through translational inhibition of Mig6 expression, Cell Discov, 2017, 第 6 作者
(3) ALU ternative regulation for gene expression, Trends Cell Biol, 2017, 第 11 作者
(4) SLERT regulates DDX21-rings associated with Pol I transcription, Cell, 2017, 第 11 作者
(5) Coordinated circRNA biogenesis and function with NF90/NF110 in viral infection, Mol Cell, 2017, 第 11 作者
(6) The diversity of long noncoding RNAs and their generation, Trends Genet, 2017, 第 11 作者
(7) Extensive translation of circular RNAs driven by N6-methyladenosine., Cell Res, 2017, 第 9 作者
(8) Enhancing the RNA engineering toolkit, Science, 2017, 第 11 作者
(9) The Output of Protein-Coding Genes Shifts to Circular RNAs When the Pre-mRNA Processing Machinery Is Limiting, Mol Cell, 2017, 第 6 作者
(10) Long Noncoding RNAs Stabilized by Small Nucleolar RNA-Protein (snoRNP) Ends, Chin J Cell Biol, 2017, 第 11 作者
(11) CircRNA-derived pseudogenes, Cell Res, 2016, 第 5 作者
(12) The biogenesis of nascent circular RNAs, Cell Reports, 2016, 第 11 作者
(13) Diverse alternative back-splicing and alternative splicing landscape of circular RNAs, Genome Res, 2016, 第 11 作者
(14) Ling-Ling Chen: Linking Long Noncoding RNA Processing and Function to RNA Biology, Trends Biochem Sci, 2016, 第 11 作者
(15) Linking Long Noncoding RNA Localization and Function, Trends Biochem Sci, 2016, 第 11 作者
(16) Characterization of circular RNAs, Methods Mol Biol, 2016, 第 11 作者
(17) The biogenesis and emerging roles of circular RNAs, Nat Rev Mol Cell Biol, 2016, 第 11 作者
(18) Shedding light on paraspeckle structure by super-resolution microscopy, J Cell Biol, 2016, 第 11 作者
(19) Research progress of long noncoding RNA in China, IUBMB Life, 2016, 第 11 作者
(20) A two-fold challenge: the experience of women of color in genomics, Genome Biol, 2016, 第 11 作者
(21) Unusual Processing Generates SPA LncRNAs that Sequester Multiple RNA Binding Proteins, Mol Cell, 2016, 第 11 作者
(22) Increased complexity of circRNA expression during species evolution, RNA Biol, 2016, 第 11 作者
(23) Fractionation of non-polyadenylated and ribosomal-free RNAs from mammalian cells, Methods Mol Biol, 2015, 第 2 作者
(24) Regulation of circRNA biogenesis, RNA Biol, 2015, 第 11 作者
(25) The long noncoding RNA regulation at the MYC locus, Curr Opin Genet Dev, 2015, 第 11 作者
(26) Gear up in circles, Mol Cell, 2015, 第 11 作者
(27) SnoVectors for nucelar expression of RNA, Nucleic Acids Res, 2015, 第 11 作者
(28) ADAR1 is required for differentiation and neural induction by regulating microRNA processing in a catalytically independent manner, Cell Res, 2015, 第 11 作者
(29) Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus, Genes Dev, 2015, 第 11 作者
(30) Scientific migration of junior scientists to China, Genome Biol, 2014, 第 11 作者
(31) Functional analysis of long noncoding RNAs in development and diseases, Adv Exp Med Biol, 2014, 第 11 作者
(32) Competition of RNA splicing: line in or circle up, Sci China Life Sci, 2014, 第 11 作者
(33) Life without A tail: new formats of long noncoding RNAs, Int J Biochem and Cell Biol, 2014, 第 11 作者
(34) Microexons go big, Cell, 2014, 第 11 作者
(35) Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions in the MYC locus, Cell Res, 2014, 第 11 作者
(36) Species-specific alternative splicing leads to unique expression of sno-lncRNAs, BMC Genomics, 2014, 第 11 作者
(37) Gene expression profiling of non-polyadenylated RNA-seq across species, Genomics Data, 2014, 第 3 作者
(38) Complementary sequence-mediated exon circularization, Cell, 2014, 第 11 作者
(39) Prediction of constitutive A-to-I editing sites from human transcriptomes in the absence of genomic sequences, BMC Genomics, 2013, 第 11 作者
(40) Circular intronic long noncoding RNAs, Mol Cell, 2013, 第 11 作者
(41) Nuclear editing of mRNA 3’-UTRs, Curr. Top. Microbiol. Immunol, 2012, 第 11 作者
(42) Long noncoding RNAs with snoRNA ends, Mol Cell, 2012, 第 11 作者
(43) Genomewide characterization of non-polyadenylated RNAs, Genome Biol, 2011, 第 11 作者
(44) Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells, Stem Cells, 2011, 第 2 作者
(45) Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cells, Cell Cycle, 2010, 第 11 作者
(46) Long non-coding RNAs in mammalian cells What Where and Why, WIREs RNA, 2010, 第 11 作者
(47) Decoding the function of nuclear long non-coding RNAs, Curr. Opin. Cell Biol, 2010, 第 11 作者
(48) Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA, Mol Cell, 2009, 第 1 作者
(49) Gene regulation by SINES and inosines: biological consequences of A-to-I editing of Alu element inverted repeats, Cell Cycle, 2008, 第 1 作者
(50) Alu element-mediated gene silencing, EMBO J, 2008, 第 1 作者
(51) On the mechanism of induction of heterochromatin by the RNA-binding protein vigilin, RNA, 2008, 第 3 作者
(52) Identification of potent type I MetAPs inhibitors by simple bioisosteric replacement, Bioorg. Med. Chem. Lett, 2005, 第 4 作者
(53) Identification of potent type I MetAP inhibitors by simple bioisosteric replacement. Part 1: Synthesis and preliminary SAR studies of thiazole-4-carboxylic acid thiazol-2-ylamide derivatives, Bioorg. Med. Chem. Lett, 2005, 第 4 作者
(54) Inhibitors of type I MetAPs containing pyridine-2-carboxylic acid thiazol-2-ylamide. Part 2: SAR studies on the pyridine ring 3-substituent, Bioorg. Med. Chem. Lett, 2005, 第 3 作者
(55) Inhibitors of type I MetAPs containing pyridine-2-carboxylic acid thiazol-2-ylamide. Part 1: SAR studies on the determination of the key scaffold, Bioorg. Med. Chem. Lett, 2005, 第 3 作者
(56) Type I methionine aminopeptidase from Saccharomyces cerevisiae is a potential target for antifungal drug screening, Acta. Pharmacol. Sin, 2004, 第 1 作者
(57) Characterization of full length and truncated type I hMetAP expressed from E. coli, Biochemistry, 2004, 第 2 作者
(58) Design and synthesis of chromogenic thiopeptolide substrates as MetAPs active site probes, Bioorg. Med. Chem. Lett, 2004, 第 3 作者
(59) Mutations at the S1 sites of methionine aminopeptidases from Escherichia coli and Homo sapiens reveal the residues critical for substrate specificity, J Biol. Chem, 2004, 第 3 作者
(60) Specificity for inhibitors of metal-substituted methionine aminopeptidase, Biochem Biophys Res Commun, 2003, 第 2 作者
(61) Discovery and structural modification of inhibitors of methionine aminopeptidases from Escherichia coli and Saccharomyces cerevisiae, J Med. Chem, 2003, 第 4 作者
(62) Studies on the apoptosis of retinal neurons following optic nerve injure in Zebrafish (Brachydanio rerio), J Lanzhou University , 2001, 第 1 作者
(63)
(1)Unconventional RNA Form & Function and beyond 2018-05-22
(2)Unconventional RNA form and function - regulation by Alu elements 2018-02-26
(3)The diversity of long noncoding RNAs, their generation and function 2018-02-18
(4)AlUternative regulation for gene expression 2018-02-12
(5)The diversity of long noncoding RNAs and their generation 谈家桢生命科学奖十周年庆典暨第十届颁奖大会,北京 2017-11-18
(6)The long noncoding RNA regulation in the nucleolus 2017-11-04
(7)Genome-wide screening of NEAT1 regulators reveals mito-paraspeckle communications 2017-10-21
(8)Biogenesis and functional implications of Circular RNAs 2017-09-26
(9)Coordinated circRNA Biogenesis and Function with NF90/NF110 in Viral Infection 第十二次全国基因功能与表观遗传调控学术研讨会,北京 2017-08-15
(10)The Diversity And Function of Long Noncoding RNAs 2017-06-14
(11)CircRNAs 2017-06-01
(12)SLERT regulates DDX21-rings associated with Pol I transcription RNA加工学术研讨会,镇江 2017-04-23
(13)The diversity of sno-processed lncRNAs and their roles in gene regulation 2017-02-08
(14)The diversity of long noncoding RNAs - their generation and function 2017-02-01
(15)The processing and functional implication of sno-processed long noncoding RNAs 2016年上海科技大学细胞生物学前沿学术研讨会,上海 2016-12-16
(16)Unusual processing generates SPA lncRNAs that sequester multiple RNA binding proteins 2016-11-17
(17)Characterization of new long noncoding RNA species 2016年上海科技大学免疫化学国际生物论坛,上海(3rd ShanghaiTech-SIAIS BioForum) 2016-11-08
(18)Sno-processed long noncoding RNAs 2016-11-07
(19)Discovery, biogenesis and functional implication of new long noncoding RNA species 2016-10-31
(20)Characterization of long noncoding RNAs in the Prader-Willi Syndrome deletion region 中国生物化学与分子生物学会2016年全国学术年会,杭州 2016-10-21
(21)Unusual processing generates sno-processed long noncoding RNAs 第九届全国核糖核酸 (RNA) 学术讨论会,上海 2016-09-27
(22)Circular RNAs 2016-09-12
(23)Unusual processing generates long noncoding RNAs with new formats 2016-08-01
(24)Unusual processing generates long noncoding RNAs with new formats 2016-08-01
(25)SPA lncRNAs 2016-06-27
(26)Biogenesis and functional studies of lncRNAs with new formats 浙江大学医学院,杭州 2016-04-15
(27)Biogenesis of long noncoding RNAs with new formats 2016-03-24
(28)Characterization of long noncoding RNAs in the Prader-Willi Syndrome deletion region 2016-03-21
(29)The biogenesis of circular RNAs 2016-02-14
(30)Biogenesis of different types of new long noncoding RNA species 中国科学技术大学生命科学学院,合肥, 中国 2015-12-16
(31)Characterization of new long noncoding RNA species: discovery, biogenesis and functional implication 2015-10-27
(32)Biogenesis and functional implication of new long noncoding RNA species 2015-10-25
(33)CircRNA biogenesis 2015-10-18
(34)CARM1 regulates mRNA nuclear retention in paraspeckles 第十一次全国基因功能与表观遗传调控学术研讨会, 上海, 中国 2015-10-13
(35)long noncoding RNA species with new formats: discovery, biogenesis and functional implication 2015-09-13
(36)Characterization of new long noncoding RNA species from the Prader-Willi Syndrome deletion region 2015-05-31
(37)New long noncoding RNA species in gene regulation 2014-10-11
(38)Complementary-sequences mediated exon circularization 2014-09-10
(39)Identification and characterization of new long noncoding RNA species 2014-07-07
(40)Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus 2014-06-03
(41)Characterization of new long noncoding RNA species 2014-06-02
(42)Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus 2014-05-05
(43)characterization of new long noncoding RNA species 2014-05-01
(44)Characterization and functional implications of new long noncoding RNA species 2014-05-01
(45)Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus 2014年春RNA研究战略研讨学术研讨会,合肥,中国 2014-04-11
(46)Life without A tail: new long noncoding RNAs from excised introns 2013-12-21
(47)New formats of long noncoding RNAs from excised introns: mechanisms and functional implications 2013-11-18
(48)Gene expression regulation by intronic long noncoding RNAs 2013-11-06
(49)Functional noncoding RNAs from excised introns 2013-10-20
(50)Functional intronic long noncoding RNAs 2013-10-09
(51)Life without (A) tail: new long noncoding RNAs from excised introns 2013-08-28
(52)Circular intronic long noncoding RNAs 2013-08-20
(53)Circular intronic long noncoding RNAs 第1次非编码RNA研究战略研讨会,北京 2013-04-12
(54)Prader-Willi Syndrome associated new long noncoding RNAs in splicing regulation in human embryonic stem cells 2012-12-03
(55)A new class of intron-derived long noncoding RNAs with snoRNA ends 2012-10-08
(56)New long noncoding RNAs in human embryonic stem cells “非编码RNA在重大生物学过程中功能和机制” 香山科学会议 2012-06-05
(57)Long noncoding RNAs with snoRNA ends 2012-04-23
(58)Intron-derived long noncoding RNAs in human embryonic stem cells 2011-12-07
(59)Altered Nuclear Retention Of MRNAS Containing Inverted Repeats In Human Embryonic Stem Cells: Functional Role Of A Nuclear Noncoding RNA Ling-Ling Chen 2009-10-30