2009-01--2015-02 Genentech Inc (Roche group) 博士后
2008-01--2009-01 麻省理工学院 博士后
2002-09--2007-12 范德堡大学 博士
2001-07--2002-06 National University of Singapore 硕士
1997-09--2001-06 北京大学 学士
学历
学位
工作经历
工作简历
2009-01~2015-02,Genentech Inc (Roche group), 博士后
2008-01~2009-01,麻省理工学院, 博士后
2002-09~2007-12,范德堡大学, 博士
2001-07~2002-06,National University of Singapore, 硕士
1997-09~2001-06,北京大学, 学士
社会兼职
教授课程
专利与奖励
奖励信息
(1) Gordon Research Conference优秀墙报奖, 一等奖, 其他, 2014
专利成果
出版信息
发表论文
(1) Synapse engineering: A new level of brain modulation., Brain Research Bulletin, 2017, 第 1 作者
(2) Development of fast neurotransmitter synapses: General principle and recent progress., Brain Research Bulletin, 2017, 第 2 作者
(3) Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function., Neuron, 2016, 第 4 作者
(4) Activity-induced Nr4a1 regulates spine density and distribution pattern of excitatory synapses in pyramidal neurons., Neuron, 2014, 第 1 作者
(5) Regulation of neuronal gene expression and survival by basal NMDA receptor activity: a role for histone deacetylase 4., J Neurosci, 2014, 第 1 作者
(6) Phosphorylation of threonine-19 of PSD-95 by GSK-3β is required for PSD-95 mobilization and long-term depression., J Neurosci, 2013, 第 4 作者
(7) Potent mGluR5 antagonists: pyridyl and thiazolyl-ethynyl-3,5-disubstituted-phenyl series., Bioorg Med Chem Lett, 2011, 第 3 作者
(8) mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning., Neuropsychopharmacology, 2009, 第 1 作者
(9) N-{4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide (CPPHA) acts through a novel site as a positive allosteric modulator of group 1 metabotropic glutamate receptors., Molecular Pharmacology, 2008, 第 1 作者
(10) nteraction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses., Molecular Pharmacology, 2007, 第 1 作者
(11) A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators., Molecular Pharmacology, 2006, 第 3 作者
(12) Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes., J Med Chem, 2006, 第 3 作者
(1)Activity--‐ induced Nr4a1 regulates spine density and distribution pattern of excitatory synapses in pyramidal neurons. Chen Y, Wang Y, Ertürk A, Kallop D, Jiang Z, Weimer RM, Kaminker J, Sheng M. 2014-06-24