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长春应用化学研究所倪嘉缵 男 博导
 

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研究领域

   

教育背景

1958-09--1961-07 前苏联科学院莫斯科普通及无机化学研究所 博士 
1949-09--1952-07 上海大同大学 学士 
学历
苏联科学院无机化学研究所 19580101--19610501 研究生毕业 
学位
苏联科学院无机化学研究所 19580101--19610501 博士 
出国学习工作
   

工作经历

   
工作简历
1952-08--今 中科院长春应用化学研究所 院士 
社会兼职
   

教授课程

生命科学进展中的化学问题

专利与奖励

   
奖励信息
   
专利成果
   

出版信息

   
发表论文
(1) Different Forms of Selenoprotein M Differentially Affect Aβ Aggregation and ROS Generation,Int. J. Mol. Sci. ,2013,通讯作者 
(2) 硒蛋白M及其与重大疾病的关系,化学进展,2013,通讯作者 
(3) 硒化聚甘露糖醛酸的合成及抗阿尔茨海默症细胞氧化与凋亡,高等学校化学学报,2013,通讯作者 
(4) Selenoprotein-Transgenic Chlamydomonas reinhardtii,Nutrients ,2013,通讯作者 
(5) Selenoprotein P and Selenoprotein M block Zn2+-mediated Aβ42 aggregation and toxicity,Metallomics,2013,通讯作者 
(6) Comparative proteomics analysis of sodium selenite-induced apoptosis in human prostate cancer cells,Metallomics,2013,通讯作者 
(7) Direct interaction of Selenoprotein R with clusterin and its possible role in Alzheimers disease,PLOS ONE,2013,通讯作者 
(8) The GO/rGO-Fe3O4 composites with good water-dispersibility and fast magnetic response for effective immobilization and enrichment of biomolecules,Journal of Materials Chemistry,2012,通讯作者 
(9) DnaJB6: an indirect interaction protein of 15-kDa Selenoprotein,Molecular Neurodegeneration,2012,通讯作者 
(10) Bioinformatic prediction of selenoprotein genes in the dolphin genome,Chinese Science Bulletin,2012,通讯作者 
(11) A facile fabrication of spherical and beanpod-like magnetic-fluorescent particles with targeting functionalities,Nanotechnology,2012,第5作者 
(12) Lanthanum silicate coated magnetic microspheres as a promising affinity material for phosphopeptide enrichment and identification,Anal Bioanal Chem,2012,通讯作者 
(13) Monodisperse REPO4 (RE=Yb, Gd, Y) Hollow Microspheres Covered with Nanothorns as Affinity Probes for Selectively Capturing and Labeling Phosphopeptides,Chemistry of a European Journal,2012,第5作者 
(14) Evolution of selenoproteins in the metazoan,BMC Genomics,2012,通讯作者 
(15) Some selenoproteins possibly involved in the development of Alzheimer’s disease: hints from the interaction proteins,Molecular Neurodegeneration,2012,通讯作者 
(16) Selenoprotein R interacts directly with Aβ1-42,Mol Neurobiol,2012,通讯作者 
(17) SelM prevents the aggregation of Ab by reducing ROS generation,Molecular Neurobiology,2012,通讯作者 
(18) Expression and characterization of a new valosin-containing protein from the silkworm,Insect Science,2012,通讯作者 
(19) 海豚基因组中硒蛋白基因的生物信息学预测,科学通报,2012,通讯作者 
(20) 人肝中硒蛋白K的相互作用蛋白的筛选与验证,高等学校化学学报,2012,通讯作者 
(21) Metabolomic profiles delineate potential roles for gadolinium chloride in the proliferation or inhibition of Hela cells,Biometals,2011,通讯作者 
(22) Synthesis of novel Fe3O4@SiO2@CeO2 microspheres with mesoporous shell for phosphopeptide capturing and labeling,Chem. Commun.,2011,第5作者 
(23) 柠檬酸镱对肝癌细胞作用差异蛋白质组学研究,中国预防医学杂志,2010,通讯作者 
(24) A new method for multi-site-directed mutagenesis,Analytical Biochemistry ,2010,通讯作者 
(25) Synthesis and characteristic of the Fe3O4@SiO2@Eu(DBM)3·H2O/SiO2 luminomagnetic microspheres with core-shell structure ,talanta,2010,第5作者 
(26) In silico identification of sea squirt selenoproteome,BMC Genomics,2010,通讯作者 
(27) Proteomic analysis of lanthanum citrate-induced apoptosis in human cervical carcinoma SiHa cells,Biometals ,2010,通讯作者 
发表著作
(1) 中国科学院稀土研究五十年,Fifty-Year-Research in Rare Earth in CAS ,科学出版社,2005-07,第2作者 
(2) 稀土生物无机化学,The Bioinorganic Chemistry of Rare Earth,科学出版社,2001-07,第1作者 
(3) 稀土新材料及新流程进展,Progress in the New Materials and Processes of Rare Earth,科学出版社,1998-07,第1作者 
(4) 稀土生物无机化学,The Bioinorganic Chemistry of Rare Earth,科学出版社,1995-07,第1作者 

科研活动

   
科研项目
(1) 若干硒蛋白及其人工模拟蛋白的构效关系,主持,国家级,2013-01--2016-12 
(2) 老年痴呆症的防治药物及其分子机理的研究,主持,市地级,2011-01--2013-12 
(3) 功能化核-壳结构磁性纳米粒子及其在分离癌细胞中的应用,主持,国家级,2009-01--2011-12 
(4) 硒化合物对预防癌症的机理研究,主持,市地级,2008-01--2011-12 
(5) 磁性纳米药物的制备及应用,主持,省级,2006-01--2008-12 
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