邓红雨研究组长期的研究方向是致瘤性病毒的复制机理以及病毒与宿主的相互作用。目前主要研究内容包括致瘤性疱疹病毒的基因表达调控、基因组复制及病毒包装的机理,致瘤性疱疹病毒与宿主细胞和免疫系统之间的相互作用,以及病毒性肝炎的致病机理等。截至目前已分别在Journal of Virology, Journal of Immunology, Virology , Blood,PLoS Pathogens等国际著名杂志发表论文近50篇。
(1) Functional identification and characterization of the nuclear egress complex of a gammaherpesvirus, J Virol, 2019-09, 通讯作者
(2) Remodeling of host membranes during herpesvirus assembly and egress, Protein Cell., 2019-05, 通讯作者
(3) Tegument protein ORF45 plays an essential role in virion morphogenesis of murine gammaherpesvirus-68, J Virol, 2016, 通讯作者
(4) The hepatitis C virus protein NS3 suppresses TNF-a–stimulated activation of NF-kB by targeting LUBAC., Sci. Signal, 2015, 通讯作者
(5) Gammaherpesvirus Tegument Protein ORF33 Is Associated with Intranuclear Capsids at an Early Stage of the Tegumentation Process, J Virol, 2015, 通讯作者
(6) Murine Gammaherpesvirus 68 ORF48 Is an RTA-Responsive Gene Product and Functions in both Viral Lytic Replication and Latency during In Vivo Infection, J Virol, 2015, 通讯作者
(7) Murine gammaherpesvirus-68 ORF38 encodes tegument protein and is packaged into virions during secondary envelopment., Protein Cell, 2014, 通讯作者
(8) Interferon-inducible cholesterol-25-hydroxylase inhibits hepatitis C virus replication via distinct mechanisms, SCIENTIFIC REPORTS, 2014, 通讯作者
(9) ZAP inhibits murine gammaherpesvirus-68 ORF64 expression and is antagonized by RTA, J Virol, 2013, 通讯作者
(10) The Virion-Associated Open Reading Frame 49 of Murine Gammaherpesvirus 68 Promotes Viral Replication both In Vitro and In Vivo as a Derepressor of RTA, J Virol, 2012, 通讯作者
(11) Zinc-finger antiviral protein inhibits murine gammaherpesvirus-68 M2 expression and regulates viral latency in cultured cells., J Virol, 2012, 通讯作者
(12) Distinct Domains in ORF52 Tegument Protein Mediate Essential Functions in Murine Gammaherpesvirus 68 Virion Tegumentation and Secondary Envelopment, Journal of Virology , 2012, 通讯作者
(13) Interferon-gamma negatively regulates Th17-mediated immunopathology during mouse hepatitis virus infection, J Mol Med, 2011, 通讯作者
(14) TNF receptor 1 mediates dendritic cell maturation and CD8 T cell response through two distinct mechanisms, J Immunology, 2011, 通讯作者
(15) CCAAT/enhancer binding proteins play a role in oriLyt dependent genome replication during murine gammaherpesvirus 68 (MHV-68) de novo infection, Protein Cell, 2011, 通讯作者
(16) Replication and Transcription Activator (RTA) of Murine Gammaherpesvirus 68 Binds to an RTA-Responsive Element and Activates the Expression of ORF18, Journal of Virology , 2011, 通讯作者
(17) Role of tegument proteins in herpesvirus assembly and egress, Protein Cell, 2010, 通讯作者
(18) Myc Is Required for the Maintenance of Kaposi Sarcoma-Associated Herpesvirus Latency , Journal of Virology , 2010, 第 4 作者
(19) RTA promoter demethylation and histone acetylation regulation of murine gammaherpesvirus 68 reactivation , PLoS One, 2009, 通讯作者
(20) Identification and functional characterization of the left origin of lytic replication of murine gammaherpesvirus-68, Virology, 2009, 通讯作者
(21) ORF33 of a gammaherpesvirus encodes a tegument protein essential for virion morphogenesis and egress, Journal of Virology, 2009, 通讯作者
(22) mRNA display design of fibronectin-based intrabodies that detect and inhibit severe acute respiratory syndrome coronavirus nucleocapsid protein, J Biol Chem, 2009, 第 4 作者
(23) Role of defective Oct-2 and OCA-B expression in immunoglobulin production and KSHV lytic reactivation in primary effusion lymphoma, Journal of Virology, 2009, 通讯作者