2011-02--今 中国科学院动物研究所 研究员
2009-04--2010-09 University of Wisconsin-Madison Assistant Scientist
2005-10--2009-03 University of Wisconsin-Madison Research Associate
2004-07--2005-10 济宁医学院 教师
1995-07--1999-07 济宁医学院 教师
教授课程
干细胞研究进展系列讲座
专利与奖励
出版信息
发表论文
(1) One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system,One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system,Cell Research,2015,第5作者
(2) Human-derived neural progenitors functionally replace astrocytes in adult mice,Human-derived neural progenitors functionally replace astrocytes in adult mice,J Clin Invest,2015,第5作者
(3) Rapid and Efficient Assembly of Transcription Activator-Like Effector Genes by USER Cloning,Rapid and Efficient Assembly of Transcription Activator-Like Effector Genes by USER Cloning,Journal of Genetics and Genomics,2014,通讯作者
(4) Induced pluripotency for translational research,Induced pluripotency for translational research,Genomics Proteomics Bioinformatics,2013,通讯作者
(5) Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice.,Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice.,Cell Stem Cell,2012,第2作者
(6) Specification of functional neurons and glia from human pluripotent stem cells.,Specification of functional neurons and glia from human pluripotent stem cells.,Protein Cell,2012,通讯作者
(7) Directed differentiation of neural-stem cells and subtype-specific neurons from hESCs.,Directed differentiation of neural-stem cells and subtype-specific neurons from hESCs.,Methods Mol Biol.,2010,第1作者
(8) Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency.,Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency.,Proc Natl Acad Sci U S A.,2010,第1作者
(9) Cre recombination-mediated cassette exchange for building versatile transgenic human embryonic stem cells lines. ,Cre recombination-mediated cassette exchange for building versatile transgenic human embryonic stem cells lines.,Stem Cells,2009,第2作者
(10) Differentiation of spinal motor neurons from pluripotent human stem cells.,Differentiation of spinal motor neurons from pluripotent human stem cells.,Nat Protoc.,2009,第1作者
(11) Differentiation of human oligodendrocytes from pluripotent stem cells.,Differentiation of human oligodendrocytes from pluripotent stem cells.,Nat Protoc.,2009,第1作者
(12) Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules.,Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules.,Stem Cells,2008,第2作者
(13) Acute photoreceptor degeneration down-regulates melanopsin expression in adult rat retina.,Acute photoreceptor degeneration down-regulates melanopsin expression in adult rat retina.,Neurosci Lett.,2006,第3作者
发表著作
(1) 新生物学年鉴2013,Advances in Biology 2013,科学出版社,2014-01,第1作者
(2) 分子生物学方法-编程与重编程章节:神经特定细胞类型定向分化,Directed differentiation of neural and subtype specific neuronal cells from hESCs. in Reprogramming and Programming of Cell Fate, Methods in Molecular Biology,Humana Press.,2009-07,第1作者
(3) 人胚干细胞实用手册章节:人胚干细胞和运动神经元定向分化,Differentiation of human embryonic stem cells into spinal motor neurons, in Human Embryonic Stem Cells: The Practical Handbook,Wiley Publishing,2007-07,第1作者
(4) 医学发育生物学章节:中枢神经系统发育,Development of Central Nervous System, in Developmental Neurobiology,科学出版社,2004-07,第1作者